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70456 Mpc2

70456

Mpc2

mitochondrial pyruvate carrier 2

protein-coding

Mus musculus

基因描述

Type Description
Definition mitochondrial pyruvate carrier 2

研究结论

Date Results Publications
2021-01-02 12:53:00 Nutritional modulation of heart failure in mitochondrial pyruvate carrier-deficient mice. 33106690
2018-05-19 10:51:00 Inhibition of pyruvate metabolism by tolylfluanid required MPC2. 29126303
2018-04-28 10:43:00 The interaction between TZDs and MPC2 is not affected by loss of the N-terminal 16 amino acid. 28597936
2017-06-10 11:47:00 MPC2 acetylation is increased in Diabetic Heart mitochondria. This study supports the conclusion that deficient pyruvate transport activity, mediated in part by acetylation of MPC2, is a contributor to metabolic inflexibility in the diabetic heart. 28154187
2015-02-28 11:07:00 Oxidative glutaminolysis supports the TCA cycle in mouse cells lacking MPC1/2. 25458843

名称对应

Type IDs
Synonymous 0610006C01Rik, 2010002I07Rik, 2610205H19Rik, AA108335, Brp44, ESTM43
Gene
UniProtKB-ID: MPC2_MOUSE
UniprotKB: Q9D023
UniParc: UPI0000003E33
EMBL: AK151522, AK002233, AK011889, BC018324
Ensembl: ENSMUSG00000026568
KO: mmu:70456
Nucleutide sequences
EMBL-CDS: BAC24983.1, BAE30471.1, AAH18324.1, BAB27898.1
Ensembl_TRS: ENSMUST00000027853
Protein sequencees
Ensembl_PRO: ENSMUSP00000027853
RefSeq: NP_081706.1
Others
UniRef100: UniRef100_Q9D023
UniRef90: UniRef90_Q9D023
UniRef50: UniRef50_Q9D023
UniGene: Mm.195625, Mm.450001
CCDS: CCDS15442.1

全选

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研究热度

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