| Type | Description |
|---|---|
| Definition | inverted formin, FH2 and WH2 domain containing |
| Date | Results | Publications |
|---|---|---|
| 2019-07-06 12:58:00 | we purified an INF2 inhibitor from mouse brain tissue, and identified it as a complex of lysine-acetylated actin (KAc-actin) and cyclase-associated protein (CAP). Inhibition of INF2 by CAP-KAc-actin is dependent on the INF2 diaphanous inhibitory domain (DID). | 30962575 |
| 2019-05-18 11:39:00 | the pathogenesis of cerebral ischemia-reperfusion injury is associated with Nurr1 upregulation followed by augmented mitochondrial fission via an abnormal YAP-INF2 pathways | 30267803 |
| 2018-08-25 12:22:00 | These data support a critical regulatory role for INF2 in trophoblast invasion-a necessary process for placentation. | 29309034 |
| 2017-10-07 13:02:00 | In mice, normal INF2 function is not required for glomerular development but normal INF2 is required for regulation of the actin-based behaviors necessary for response to and/or recovery from injury. | 27350175 |
| 2017-07-29 10:59:00 | Data highlight a unique mechanism of formin action in which mDia1 and INF2 function in series to stabilize MTs and point to IQGAP1 as a scaffold that facilitates the activation of one formin by another. | 27030671 |
| Type | IDs |
|---|---|
| Synonymous | 2610204M08Rik, AA589465, AW125550, EG629699 |
| Gene |
UniProtKB-ID:
INF2_MOUSE,
E9QLA5_MOUSE
UniprotKB:
Q0GNC1,
E9QLA5
UniParc:
UPI0000DE2389,
UPI000176163C,
UPI0000DD52F0
EMBL:
BC115422,
BC099931,
BC115423,
DQ834374,
AC124373,
BC060610
Ensembl:
ENSMUSG00000037679
KO:
mmu:70435
|
| Nucleutide sequences |
EMBL-CDS:
AAH60610.1,
AAI15423.2,
AAI15424.2,
AAH99931.1,
ABI20145.1
Ensembl_TRS:
ENSMUST00000101029
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000098591
RefSeq:
XP_030102769.1,
NP_001361128.1,
XP_030102767.1,
XP_030102765.1,
XP_030102770.1,
NP_940803.2,
XP_036013503.1,
XP_030102766.1
|
| Others |
UniRef100:
UniRef100_Q0GNC1,
UniRef100_E9QLA5
UniRef90:
UniRef90_Q0GNC1
UniRef50:
UniRef50_Q0GNC1
UniGene:
Mm.250193
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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