| Type | Description |
|---|---|
| Definition | multiple EGF-like-domains 10 |
| Date | Results | Publications |
|---|---|---|
| 2020-05-16 12:21:00 | We find that tubular muscle subtypes are particularly sensitive to Megf10/Drpr overexpression. Complementary genetic analyses show that Megf10/Drpr and Notch may interact to regulate myogenesis. Our findings provide a basis for investigating MEGF10 in muscle development using Drosophila. | 30802937 |
| 2018-05-05 10:10:00 | Results indicate that Multiple-EGF like domains 10 (MEGF10)may be responsible for phagocytic activity targeted toward unwanted substances such as amyloid in cholinergic and glutamatergic neurons. | 28526325 |
| 2017-07-01 11:07:00 | Megf10 binds with high affinity to C1q, an eat-me signal for apoptotic cells. Cells expressing Megf10 with EMARDD mutations have impaired apoptotic cell clearance and impaired binding to C1q. | 27170117 |
| 2014-01-25 10:37:00 | studies reveal a novel role for astrocytes in mediating synapse elimination in the developing and adult brain, identify MEGF10 and MERTK as critical proteins in the synapse remodelling underlying neural circuit refinement | 24270812 |
| 2013-11-16 11:54:00 | Cysteine mutations cause defective tyrosine phosphorylation in MEGF10 myopathy. | 23954233 |
| Type | IDs |
|---|---|
| Synonymous | 3000002B06Rik, Gm331 |
| Gene |
UniProtKB-ID:
MEG10_MOUSE
UniprotKB:
Q6DIB5
UniParc:
UPI00003BA2FC
EMBL:
AK148084,
AK147238,
AK166316,
BC075647
Ensembl:
ENSMUSG00000024593
KO:
mmu:70417
|
| Nucleutide sequences |
EMBL-CDS:
BAE27788.1,
BAE28336.1,
AAH75647.1,
BAE38699.1
Ensembl_TRS:
ENSMUST00000075770
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000075174
RefSeq:
NP_001001979.1
|
| Others |
UniRef100:
UniRef100_Q6DIB5
UniRef90:
UniRef90_Q96KG7
UniRef50:
UniRef50_Q96KG7
UniGene:
Mm.297863
CCDS:
CCDS29264.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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