例如:"NBL1", "4681", "drought"
收藏
7035 TFPI

7035

TFPI

tissue factor pathway inhibitor

protein-coding

Homo sapiens

基因描述

Type Description
Definition tissue factor pathway inhibitor

研究结论

Date Results Publications
2020-08-15 19:05:00 Transcription factor FOXP3: A repressor of the TFPI gene? 30861202
2020-08-01 14:20:00 Data identify POU1F1 as a transcription factor that regulates TFPI transcription in response to ADTRP, and link POU1F1 variants to risk of CAD for the first time. 32445923
2019-12-14 12:13:00 Novel MASP-2 inhibitors developed via directed evolution of human TFPI1 are potent lectin pathway inhibitors. 30952698
2019-09-21 10:22:00 FV (and particularly its FV2 isoform) contributes to the TFPIalpha-dependent down-regulation of thrombin generation in plasma triggered with low TF. 29864781
2019-06-22 11:56:00 under flow, TFPI-alpha is capable to antagonize fibrin formation in a manner dependent on and restricted by local TF/factor VIIa and factor Xa activities 29452445

名称对应

Type IDs
Synonymous EPI, LACI, TFI, TFPI1
Gene
UniProtKB-ID: TFPI1_HUMAN
UniprotKB: P10646
UniParc: UPI000002B533, UPI0000136C8F
EMBL: J03225, M58645, AC007319, M58644, CH471058, M59499, M59498, AF021834, M58648, M59493, BC015514, M58647, M58650, M59494, M59495, M59496, M58649, AY263365, M59497, M58646
Ensembl: ENSG00000003436
KO: hsa:7035
Nucleutide sequences
EMBL-CDS: AAY14807.1, EAX10921.1, AAA59526.1, AAO89075.1, EAX10922.1, AAA52022.1, AAD01700.1, AAA59480.1, AAH15514.1
Ensembl_TRS: ENST00000339091, ENST00000392365, ENST00000409676, ENST00000233156
Protein sequencees
Ensembl_PRO: ENSP00000342306, ENSP00000386344, ENSP00000376172, ENSP00000233156
RefSeq: XP_024308828.1, NP_001316170.1, XP_024308830.1, XP_024308829.1, XP_024308826.1, XP_024308827.1, NP_001027452.1, NP_001305870.1, NP_001316169.1, NP_006278.1, XP_011510011.1, NP_001316168.1, XP_006712783.1
Others
UniRef100: UniRef100_P10646
UniRef90: UniRef90_P10646
UniRef50: UniRef50_P10646
UniGene: Hs.516578
CCDS: CCDS2294.1, CCDS33349.1

全选

{{proteinIndex+1}}
mRNA Protein UniprotKB Description
Refseq {{protein.nucleotideVersion}}

Ensembl: {{protein.nucleotideEnsembl}}

{{protein.proteinVersion}}

Ensembl: {{protein.proteinEnsembl}}

{{uniprot}}
Definition: {{{protein.definition}}}

Transcript Veriant:{{protein.transcriptVeriant}}

Status: {{protein.status}}

Location ( {{protein.positionStart}}..{{protein.positionEnd}} )

暂无数据

研究热度

热点单位
排名 科研单位 文献
{{affIndex+1}}

{{aff.value}}

{{aff.size}}

目前还没有研究热点单位

热点人员
排名 研究人员 文献
{{authorIndex+1}}

{{author.value}}

{{author.size}}

目前还没有研究热点人员