| Type | Description |
|---|---|
| Definition | fuzzy planar cell polarity protein |
| Date | Results | Publications |
|---|---|---|
| 2017-06-03 12:20:00 | This paper reports a novel skull phenotype in a ciliopathic mutant mouse in which only a single calvarial bone plate encases the forebrain in mice lacking Fuz, an essential regulator of ciliogenesis. | 27395007 |
| 2013-09-14 10:09:00 | Fuzzy appears to control subcellular localization of the core PCP protein Dishevelled, recruiting it to Rab8-positive vesicles and to the basal body and cilium. We show that loss of Fuzzy results in inhibition of PCP signaling | 23303251 |
| 2013-09-07 11:44:00 | Using the ciliopathic Fuz mutant mouse, we find that high arched palate does not, as commonly suggested, arise from midface hypoplasia; rather, increased neural crest expands the maxillary primordia. | 23806618 |
| 2012-05-19 10:47:00 | Data report the dynamic expression of another planar cell polarity gene, Fuzzy, during neural tube formation in mice. | 21840926 |
| 2012-03-03 11:15:00 | The data demonstrate a new model for coordination of Hh and Wnt signaling and reveal a Fuz-dependent negative feedback loop controlling Wnt/beta-catenin signaling. | 21935430 |
| Type | IDs |
|---|---|
| Synonymous | 2600013E07Rik, b2b1273Clo |
| Gene |
UniProtKB-ID:
FUZZY_MOUSE,
A0A140LI55_MOUSE,
E9QL29_MOUSE
UniprotKB:
Q3UYI6,
A0A140LI55,
E9QL29
UniParc:
UPI0001F793F7,
UPI00016277AD,
UPI0000428DE6,
UPI000000B886
EMBL:
AK011195,
AK134650,
AC158231,
BC045601
Ensembl:
ENSMUSG00000011658
KO:
mmu:70300
|
| Nucleutide sequences |
EMBL-CDS:
BAE22226.1,
AAH45601.1,
BAB27459.1
Ensembl_TRS:
ENSMUST00000209132,
ENSMUST00000209039,
ENSMUST00000071207
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000146434,
ENSMUSP00000146681,
ENSMUSP00000071194
RefSeq:
XP_006541255.1,
XP_006541256.1,
NP_081652.2,
XP_006541257.1
|
| Others |
UniRef100:
UniRef100_A0A140LI55,
UniRef100_Q3UYI6,
UniRef100_E9QL29
UniRef90:
UniRef90_Q3UYI6,
UniRef90_Q3B756-2
UniRef50:
UniRef50_Q3B756-2,
UniRef50_Q3UYI6
UniGene:
Mm.276298
CCDS:
CCDS52237.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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