| Type | Description |
|---|---|
| Definition | actin filament associated protein 1 |
| Date | Results | Publications |
|---|---|---|
| 2015-08-01 10:48:00 | These data define, for the first time, the requirement of AFAP1 for the spatial and temporal regulation of cSrc activity in the normal breast, specifically for milk production. | 25043309 |
| 2010-01-21 00:00:00 | In E16 mouse embryos, AFAP expression levels concentrated in the olfactory bulb, cortex, forebrain, cerebellum, and various peripheral sensory structures.In P3 mouse pups, overall expression was reduced. (AFAP-110) | 12532398 |
| 2010-01-21 00:00:00 | AFAP120 may coordinate Src signaling with the dynamic changes in the actin cytoskeleton that drive growth cone motility and axon elongation. | 18723076 |
| 2010-01-21 00:00:00 | These results indicate that AFAP120 plays a role in organizing dynamic actin structures during neuronal differentiation and suggest that AFAP120 may help regulate the transition from motile precursor to morphologically differentiated neurons. | 19281763 |
| 2010-01-21 00:00:00 | Actin filament associated protein-110 (AFAP) colocalizes with cSrc to promote cSrc activation and cell migration. | 17360811 |
| Type | IDs |
|---|---|
| Synonymous | 2600003E23Rik, 9630044L16Rik, AI848729, Afap, mKIAA3018 |
| Gene |
UniProtKB-ID:
AFAP1_MOUSE
UniprotKB:
Q80YS6
UniParc:
UPI000018CE1E
EMBL:
AK147706,
AK161385,
AK129483,
BC050814,
AK148000
Ensembl:
ENSMUSG00000029094
KO:
mmu:70292
|
| Nucleutide sequences |
EMBL-CDS:
BAE28280.1,
AAH50814.1,
BAC98293.1,
BAE28086.1,
BAE36364.1
Ensembl_TRS:
ENSMUST00000064571
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000067779
RefSeq:
NP_081649.1,
XP_030110659.1,
XP_030110660.1,
XP_006504161.1
|
| Others |
UniRef100:
UniRef100_Q80YS6
UniRef90:
UniRef90_Q8VH46
UniRef50:
UniRef50_Q90738-2
UniGene:
Mm.125167
CCDS:
CCDS19236.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 29254152 |
Oncotarget Maria Del Mar Masdeu , Beatriz G Armendáriz , Anna La Torre , Eduardo Soriano , Ferran Burgaya , Jesús Mariano Ureña |
2017-11-24 | - |
| 25043309 |
Oncogene J M Cunnick , S Kim , J Hadsell , S Collins , C Cerra , P Reiser , D C Flynn , Y Cho |
2015-05-14 |
Src,
Afap1
|
| 24154525 |
Development Jeremy A Miller , Jason Nathanson , Daniel Franjic , Sungbo Shim , Rachel A Dalley , Sheila Shapouri , Kimberly A Smith , Susan M Sunkin , Amy Bernard , Jeffrey L Bennett , Chang-Kyu Lee , Michael J Hawrylycz , Allan R Jones , David G Amaral , Nenad Å estan , Fred H Gage , Ed S Lein |
2013-11-01 |
Rpp25,
Gldc,
Rhoq,
Psat1,
Tm6sf1,
Slc14a1,
Rimklb,
Nusap1,
Mybpc1,
Npy,
Bmp3,
Adgrv1,
Dlx1as,
Acadl,
Laptm4b,
Pawr,
Adra1a,
Alcam,
Aldoc,
Necab2,
Ank1,
Apoe,
Nr2f2,
Aqp4,
Rnd2,
Arnt2,
Bcan,
Bcat1,
Fabp7,
Zfp36l1,
C1qc,
Calb2,
Capn2,
Car2,
Cbln2,
Cbs,
Ccnd2,
Cd24a,
Entpd2,
Cd63,
Cd81,
Cd9,
Cdh11,
Cdh5,
Cit,
Ckb,
Cldn5,
Clu,
Cnp,
Cnr1,
Col19a1,
Col9a3,
Cort,
Cox6a2,
Cplx1,
Hapln1,
Cryab,
Csrp1,
Cst3,
Ctsd,
Ctsl,
Ctss,
Cux2,
Dbi,
Dcx,
Asap1,
Dio2,
Dlx1,
Cdk2ap1,
Ect2,
Egfr,
Eps8,
Erbb4,
Eya4,
Elmo1,
Fasn,
Fgf12,
Fgfr1,
Gaa,
Gabrg3,
Gad1,
Gad2,
Gap43,
Gfap,
Gpr83,
Gja1,
Gjd2,
Glul,
Glrb,
Gnai1,
Gnas,
Got1,
Adgrg1,
Cdca3,
Gria4,
Grik1,
Grpr,
Hbb-b1,
Hbb-b2
|
| 23431145 |
The protomap is propagated to cortical plate neurons through an Eomes-dependent intermediate map. Proc. Natl. Acad. Sci. U.S.A. Gina E Elsen , Rebecca D Hodge , Francesco Bedogni , Ray A M Daza , Branden R Nelson , Naoko Shiba , Steven L Reiner , Robert F Hevner |
2013-03-05 |
Nxph4,
Etv5,
Aldh1l1,
Lmo1,
Tshz1,
Kcnq3,
Chrna7,
Adcyap1,
Bcan,
Bcl6,
Cck,
Cckar,
Cdh11,
Cdh8,
Cdkn1c,
Crabp1,
Crym,
Dct,
Elk3,
Emx2,
Eomes,
Nr2f1,
Etv1,
Fgfr3,
Gnal,
Hey1,
Slc6a4,
Lef1,
Lhx9,
Lmo4,
Mc4r,
Mest,
Ncam2,
Nefl,
Nefm,
Nhlh2,
Nin,
Nr4a3,
Nrp2,
Pax6,
Ppp1r1b,
Stab2,
Ptpro,
Abcd4,
Robo1,
Sema5a,
Six2,
Ncor2,
Stat3,
Tbr1,
Tcf4,
Lrrtm3,
Zfp521,
Rorb,
Dner,
Tshz2,
Mmp17,
Tenm2,
Tenm3,
Spry2,
Actr3b,
Plxna4,
Map2k6,
Robo2,
Nrip1,
Fat3,
Prex1,
Dusp4,
Auts2,
Sp8,
Cdh10,
Mical2,
Htra1,
Dusp14,
Bhlhe22,
Sv2b,
Lima1,
Dnajc15,
Rgcc,
Fam210b,
Cap2,
1190002N15Rik,
Afap1,
Fgfbp3,
Rnd3,
Vit,
0610040J01Rik,
Ube2ql1,
Prdm8,
Nav2,
Cemip,
Tmem2
|
| 21873635 |
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas |
2011-09-01 | - |
| 21677750 |
A conditional knockout resource for the genome-wide study of mouse gene function. Nature William C Skarnes , Barry Rosen , Anthony P West , Manousos Koutsourakis , Wendy Bushell , Vivek Iyer , Alejandro O Mujica , Mark Thomas , Jennifer Harrow , Tony Cox , David Jackson , Jessica Severin , Patrick Biggs , Jun Fu , Michael Nefedov , Pieter J de Jong , A Francis Stewart , Allan Bradley |
2011-06-15 | - |
| 19281763 |
AFAP120 regulates actin organization during neuronal differentiation. Differentiation Xiaohua Xu , Jennifer Harder , Daniel C Flynn , Lorene M Lanier |
2009-01-01 | - |
| 18723076 |
Neurosci Lett Jennifer Harder , Xiaohua Xu , Paul Letourneau , Lorene M Lanier |
2008-10-24 | - |
| 18799693 |
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Genome Res. Gwenn M Hansen , Diane C Markesich , Michael B Burnett , Qichao Zhu , Karen M Dionne , Lizabeth J Richter , Richard H Finnell , Arthur T Sands , Brian P Zambrowicz , Alejandro Abuin |
2008-10-01 |
Gm11335,
Gm17762,
A930017K11Rik,
BC028777,
Gm13999,
Gm11696,
Gm12359,
Gm10589,
D030047H15Rik,
Gm10856,
Gm10685,
Gm10062,
Gm10433,
Gm10648,
Gm10840,
Gm15441,
Gm10684,
Gm9900,
Gm10822,
Gm10687,
Gm11744,
Gm10747,
Arih2os,
B230344G16Rik,
Fmr1os,
Tmem51os1,
Gm14488,
Gm13033,
Gm10789,
Gm10615,
Gm1976,
Gm9967,
Gm9917,
Gm1974,
Gm11496,
Gm13580,
Gm2085,
Gm2183,
Gm2245,
Tbx3os1,
Gm12980,
Gm2329,
Lncenc1,
Gm2381,
Snhg12,
Gm2479,
Gm12942,
Gm2529,
Gm2533,
Rpl30-ps7,
Rsf1os2,
Gm2695,
2810416G20Rik,
Rpl30-ps6,
Gm2773,
Gm2788,
Dynlt1f,
Gm9793,
Gm2885,
Gm2920,
Gm15506,
Gm11627,
Gm10518,
Gm13496,
Gm3134,
Gm12827,
Gm3143,
Gm10144,
Ahnak2,
Gm3196,
Gm13242,
Gm3325,
Gm13247,
Gm10863,
Gm13157,
4930522L14Rik,
Gm3552,
Gm15226,
Gm3604,
Gm3643,
BC005561,
Gm3716,
2810410L24Rik,
Gm10282,
Gm3839,
Nhsl2,
4732419C18Rik,
Gm3906,
Gm3973,
Gm4013,
Apol7d,
Gm12057,
Gm10489,
Rex2,
1110002L01Rik,
Gm4189,
Gm4204,
4632428C04Rik,
9130023H24Rik
|
| 18725516 |
Single-cell gene profiling defines differential progenitor subclasses in mammalian neurogenesis. Development Ayano Kawaguchi , Tomoko Ikawa , Takeya Kasukawa , Hiroki R Ueda , Kazuki Kurimoto , Mitinori Saitou , Fumio Matsuzaki |
2008-09-01 |
C230098O21Rik,
Aif1l,
Arx,
Neurod6,
Neurog2,
Serping1,
Ccna1,
Ccnb2,
Dab1,
Dcx,
Dll1,
Dll3,
Ednrb,
Eomes,
Slc17a6,
Fgfr2,
Fgfr3,
Fstl1,
Gli3,
Elavl2,
Elavl4,
Igfbp5,
Lrp8,
Lrrn3,
Mfge8,
Mfng,
Mki67,
Cited2,
Myt1,
Neurod1,
Nsg2,
Rpa2,
Cxcl12,
Sfrp2,
Slc1a3,
Sstr2,
Sox11,
Sox9,
Sdc3,
Sertad4,
Fam167a,
Vcam1,
AI504432,
Sorbs2,
Coro1c,
Gadd45g,
Mgat5b,
Ccnb1,
Lrrc16b,
Acot1,
Fkbp9,
Ndrg2,
Sybu,
Rasgef1b,
A730054J21Rik,
Insm1,
Hes6,
Olfm1,
Ttyh1,
Ppp1r1a,
Trp53inp1,
Rwdd3,
Soga3,
Ccdc80,
Nrn1,
Trp53inp2,
Ddah1,
Gpx8,
Afap1,
Uaca,
Clvs1,
9430087N24Rik
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
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| 排名 | 研究人员 | 文献 |
|---|---|---|
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