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7021 TFAP2B

7021

TFAP2B

transcription factor AP-2 beta

protein-coding

Homo sapiens

基因描述

Type Description
Definition transcription factor AP-2 beta

研究结论

Date Results Publications
2020-06-27 11:04:00 TFAP2B bound to the promoter of COX-2 to activate its expression, indicating that TFAP2B is a critical regulatory molecule in the COX-2 signaling pathway that promoted tumor progression in thyroid cancer. 31113934
2020-06-06 11:37:00 PKD knockdown in human umbilical vein endothelial cells increases binding of AP2beta to the VEGFR-2 promoter. 31492751
2020-04-04 11:09:00 Mutations in TFAP2B and previously unimplicated genes of the BMP, Wnt, and Hedgehog pathways in syndromic craniosynostosis have been reported. 31292255
2020-02-05 12:29:00 AP-2beta is a binding partner for DHX33 which acts as a coactivator for AP-2beta to promote the transcription of antiapoptotic Bcl-2 gene. 31182639
2019-08-17 10:50:00 A polymorphic Alu in the flanking region of the TFAP2B and TFAP2D genes has been identified. The new insert was found in higher frequency in Europeans (0.4) and Asians (0.38) and lower frequency in Africans (0.25). 30975199

名称对应

Type IDs
Synonymous AP-2B, AP2-B, PDA2
Gene
UniProtKB-ID: AP2B_HUMAN
UniprotKB: Q92481
UniParc: UPI000020DE90, UPI000020DE92
EMBL: Y09912, X95694, AL031224, AJ278356, AL049693, BC037225
Ensembl: ENSG00000008196
KO: hsa:7021
Nucleutide sequences
EMBL-CDS: CAC01130.1, CAA64990.1, AAH37225.2, CAA71047.1
Ensembl_TRS: ENST00000393655
Protein sequencees
Ensembl_PRO: ENSP00000377265
RefSeq: XP_011513139.1, NP_003212.2, XP_016866724.1, XP_016866722.1, XP_016866723.1
Others
UniRef100: UniRef100_Q92481
UniRef90: UniRef90_Q92481
UniRef50: UniRef50_Q92481
UniGene: Hs.33102
CCDS: CCDS4934.2

全选

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研究热度

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