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70086 Cysltr2

70086

Cysltr2

cysteinyl leukotriene receptor 2

protein-coding

Mus musculus

基因描述

Type Description
Definition cysteinyl leukotriene receptor 2

研究结论

Date Results Publications
2019-08-31 11:41:00 this study shows that cysteinyl leukotriene receptor 2 drives lung immunopathology through a platelet and high mobility box 1-dependent mechanism 30664709
2019-01-19 12:38:00 CysLT2 receptors were constitutively expressed in the lung, and expression was strengthened in asthmatic mice. Activation of CysLT2 receptors was functionally involved in allergic leukocyte infiltration into the lung. 29628047
2018-10-06 11:37:00 CysLT2R signaling, IL-33-dependent group 2 innate lymphoid cell expansion, and IL-33-driven mast cell activation are necessary for induction of type 2 immunopathology and aspirin sensitivity. CysLT2R-targeted drugs may interrupt these processes. 29282304
2014-10-04 10:58:00 It plays a critical role in Ab1e42-induced neurotoxicity. 24269024
2014-07-26 12:45:00 The CysLT(1) and CysLT(2) receptors were primarily localized in neurons, microglia and neutrophils 23132680

名称对应

Type IDs
Synonymous 2300001H05Rik, CYSLT2R, Cltr2, Cyslt2
Gene
UniProtKB-ID: CLTR2_MOUSE
UniprotKB: Q920A1
UniParc: UPI0000025DB4
EMBL: BC132418, CH466535, BC132414, AF331658
Ensembl: ENSMUSG00000033470
KO: mmu:70086
Nucleutide sequences
EMBL-CDS: AAK97354.1, EDL35864.1, AAI32419.1, AAI32415.1, EDL35865.1
Ensembl_TRS: ENSMUST00000169168, ENSMUST00000044664
Protein sequencees
Ensembl_PRO: ENSMUSP00000040715, ENSMUSP00000125958
RefSeq: NP_001155884.1, NP_598481.2, XP_030103861.1
Others
UniRef100: UniRef100_Q920A1
UniRef90: UniRef90_Q920A1
UniRef50: UniRef50_Q920A1
UniGene: Mm.158324
CCDS: CCDS27265.1

全选

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研究热度

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