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70025 Acot7

70025

Acot7

acyl-CoA thioesterase 7

protein-coding

Mus musculus

基因描述

Type Description
Definition acyl-CoA thioesterase 7

研究结论

Date Results Publications
2020-04-04 11:36:00 Acot7, a fatty acid metabolic enzyme highly enriched in neurons, regulates both brain-specific metabolic processes related to seizure susceptibility and the whole body response to dietary lipid 31039008
2018-01-20 10:03:00 downstream effects of LPS-induced induction of ACOT7 and its role in inflammatory settings in myeloid cells 28416579
2017-06-10 11:28:00 Data (including data from studies in transgenic mice) suggest that up-regulation of Acot7 expression in clonal beta-cells impairs insulin secretion in response to glucose plus free fatty acids; expression of Acot7 is ubiquitous across tissues but relatively silenced/disallowed in pancreatic beta cells. 26861785
2014-02-01 12:23:00 ACOT7 may be involved in dietary intake-associated responses in fatty acid metabolism in mesenteric lymph nodes. 23649344
2013-06-01 10:06:00 ACOT7 counterregulates fatty acid metabolism in neurons and protects against neurotoxicity. 23459938

名称对应

Type IDs
Synonymous 2410041A17Rik, Ach1, Act, Bach, CTE-IIa, Cte-II, Lach1
Gene
UniProtKB-ID: BACH_MOUSE, E9PYH2_MOUSE
UniprotKB: Q91V12, E9PYH2
UniParc: UPI00019865DA, UPI000002A4B4, UPI0000029505, UPI0000029029, UPI0000194FEB
EMBL: AL772240, AB088411, AL611985, BC013507, AB049821, AL671869, AB207243, AK152277, AB088412
Ensembl: ENSMUSG00000028937
KO: mmu:70025
Nucleutide sequences
EMBL-CDS: BAE31092.1, AAH13507.1, BAB61731.1, BAC20218.1, BAD91166.1, BAC20217.1
Ensembl_TRS: ENSMUST00000030779, ENSMUST00000105652, ENSMUST00000075363, ENSMUST00000167926
Protein sequencees
Ensembl_PRO: ENSMUSP00000074827, ENSMUSP00000030779, ENSMUSP00000101277, ENSMUSP00000129121
RefSeq: NP_001356205.1, NP_001356203.1, XP_030109628.1, NP_001356204.1, XP_036020303.1, NP_001356202.1, XP_030109629.1, NP_001139529.2, XP_006539232.1, NP_001139530.1, XP_030109627.1, NP_579926.2
Others
UniRef100: UniRef100_Q91V12
UniRef90: UniRef90_Q91V12
UniRef50: UniRef50_Q91V12
UniGene: Mm.296191
CCDS: CCDS51390.1, CCDS51391.2, CCDS51392.1

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