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6993 DYNLT1

6993

DYNLT1

dynein light chain Tctex-type 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition dynein light chain Tctex-type 1

研究结论

Date Results Publications
2020-04-04 11:11:00 Beclin1 mRNA and protein were significantly increased in spermatozoa from infertile patients of different etiologies in comparison to healthy controls. However, DYNLT1 mRNA expression was significantly decreased in infertile groups than controls. Mature spermatozoa extracted from all studied subjects showed increased DYNLT1 mRNA and decreased Beclin1 mRNA and protein expression compared with the whole sample. 31382319
2019-10-05 10:21:00 expression of Tctex-1 T94E did not influence KIM-1-mediated efferocytosis 29693725
2019-08-17 11:07:00 MAP4 and Tctex-1 play important roles in regulating the migration of epidermal cells under hypoxia. 30091292
2019-04-06 12:57:00 siRNA silencing of Tctex1 suppressed cellular viability and promoted cell apoptosis. Protein and mRNA expression of Tctex1 and dynein decreased after Tctex1 knockdown, whereas alpha-synuclein, LC3-II, and LAMP2 increased. Consistently, fluorescence intensity of Tctex1 was weaker in siRNA-Tctex1-transfected cells, and that of alpha-synuclein, LC3-II, and LAMP2 was increased. 29406369
2018-07-28 11:20:00 Tctex1 overexpression promoted autophagy lysosome fusion and effectively degraded alpha-synuclein with increased cell activity 28970129

名称对应

Type IDs
Synonymous CW-1, TCTEL1, tctex-1
Gene
UniProtKB-ID: DYLT1_HUMAN
UniprotKB: P63172
UniParc: UPI00000012DB
EMBL: EU862237, D50663, AL591025, BC105588, BC029412, AK315601, U56255, CR456931, CH471051, AL589931
Ensembl: ENSG00000146425
KO: hsa:6993
Nucleutide sequences
EMBL-CDS: ACF74976.1, AAH29412.1, EAW47657.1, CAG33212.1, AAB03318.1, AAI05589.1, BAG37971.1, BAA09317.1
Ensembl_TRS: ENST00000367089
Protein sequencees
Ensembl_PRO: ENSP00000356056
RefSeq: NP_006510.1, NP_001278531.1, NP_001278532.1
Others
UniRef100: UniRef100_P63172
UniRef90: UniRef90_P63172
UniRef50: UniRef50_P63172
UniGene: Hs.445999
CCDS: CCDS5257.1

全选

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