| Type | Description |
|---|---|
| Definition | protein phosphatase 1 regulatory inhibitor subunit 11 |
| Date | Results | Publications |
|---|---|---|
| 2017-11-26 00:16:00 | Lentiviral gene transfer or knockdown of PPP1R11 in mouse lungs significantly affects lung inflammation and the clearance of Staphylococcus aureus. There is a negative correlation between PPP1R11 and TLR2 levels in white blood cell samples isolated from patients with Staphylococcus aureus infections | 27805901 |
| 2015-02-14 12:59:00 | a model in which I3 regulates an SDS22-mediated PP1 activation step in solution that precedes SDS22 dissociation and transfer of PP1 to kinetochores, and which is required for PP1 to efficiently antagonize Aurora B. | 25298395 |
| 2010-01-21 00:00:00 | Sds22 and Inhibitor-3 form a heterotrimeric complex with PP1, both in cell lysates and after purification. A pool of PP1 is complexly controlled by both Sds22 and Inhibitor-3. | 17630778 |
| 2010-01-21 00:00:00 | inhibitor-3 is an in vivo target of caspase-3 and participates in the apoptotic response | 18450750 |
| 2010-01-21 00:00:00 | Inh3 has two domains that are required for its interaction with PP1. | 18951879 |
| Type | IDs |
|---|---|
| Synonymous | CFAP255, HCG-V, HCGV, IPP3, TCTE5, TCTEX5 |
| Gene |
UniProtKB-ID:
PP1RB_HUMAN,
A2BEK1_HUMAN
UniprotKB:
O60927,
A2BEK1
UniParc:
UPI000000D734
EMBL:
U53588,
AL845439,
BC102011,
X81003,
KY500568,
AB088087,
AL669914,
CH471081,
X89902,
KY500569,
BA000025,
AK313175,
BC104750,
AB202082,
BC102010,
AL671859
Ensembl:
ENSG00000236560,
ENSG00000204619,
ENSG00000233314,
ENSG00000237829,
ENSG00000237403,
ENSG00000206501,
ENSG00000227720,
ENSG00000234058
KO:
hsa:6992
|
| Nucleutide sequences |
EMBL-CDS:
AAI02011.1,
AAI02012.1,
BAC54919.1,
CAC16920.1,
BAB63334.1,
BAE78601.1,
AAI04751.1,
AAC52082.1,
CAC16919.1,
EAX03253.1,
AQY77041.1,
BAG35992.1,
AQY77040.1
Gene_ORFName:
hCG_23774
Ensembl_TRS:
ENST00000452679,
ENST00000376772,
ENST00000448378,
ENST00000431977,
ENST00000437937,
ENST00000436591,
ENST00000431424,
ENST00000383612
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000407981,
ENSP00000411038,
ENSP00000373107,
ENSP00000365963,
ENSP00000414808,
ENSP00000394056,
ENSP00000412297,
ENSP00000403557
RefSeq:
XP_006715237.1,
NP_068778.1
|
| Others |
UniRef100:
UniRef100_O60927
UniRef90:
UniRef90_O60927
UniRef50:
UniRef50_O60927
UniGene:
Hs.82887
CCDS:
CCDS4671.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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