| Type | Description |
|---|---|
| Definition | BUB1 mitotic checkpoint serine/threonine kinase |
| Date | Results | Publications |
|---|---|---|
| 2021-02-02 13:29:00 | BUB1 and CENP-U, Primed by CDK1, Are the Main PLK1 Kinetochore Receptors in Mitosis. | 33248027 |
| 2020-12-26 13:13:00 | SET/TAF1 forms a distance-dependent feedback loop with Aurora B and Bub1 as a tension sensor at centromeres. | 32973131 |
| 2020-10-24 14:03:00 | Untangling the contribution of Haspin and Bub1 to Aurora B function during mitosis. | 32027339 |
| 2020-08-13 18:50:00 | Histone H2A phosphorylation recruits topoisomerase IIalpha to centromeres to safeguard genomic stability. | 31769059 |
| 2020-04-25 11:11:00 | Here, we present for the first time the identification and the preclinical profile of the novel BUB1 kinase inhibitor BAY 1816032. In particular, we demonstrate additive and more than additive efficacy upon combination of BUB1 kinase inhibition with taxanes, as well as with inhibitors in cellular and in tumor xenograft models. | 30429199 |
| Type | IDs |
|---|---|
| Synonymous | BUB1A, BUB1L, hBUB1 |
| Gene |
UniProtKB-ID:
BUB1_HUMAN,
B4DYG2_HUMAN
UniprotKB:
O43683,
B4DYG2
UniParc:
UPI00000012C4,
UPI0001639AF5,
UPI0002065A5F,
UPI00017A82A2
EMBL:
AC114776,
AF139354,
AF139361,
AF139363,
AF139356,
AF139357,
AF043294,
AF139352,
AF046078,
AF139359,
AC226101,
AF139358,
BC028201,
AK302418,
AF139353,
AF139350,
AF139362,
AF053305,
AF047471,
CH471237,
AF139351,
AF139355,
AF139349,
AF139360,
AF011387
Ensembl:
ENSG00000169679
KO:
hsa:699
|
| Nucleutide sequences |
EMBL-CDS:
AAB97855.2,
EAW50355.1,
AAC06259.1,
AAD43675.1,
AAC39546.1,
AAC12729.1,
AAH28201.1,
AAY14706.1,
AAC03122.1,
BAG63724.1
Ensembl_TRS:
ENST00000535254,
ENST00000302759,
ENST00000409311
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000441013,
ENSP00000302530,
ENSP00000386701
RefSeq:
NP_004327.1,
NP_001265545.1,
NP_001265546.1
|
| Others |
UniRef100:
UniRef100_O43683,
UniRef100_B4DYG2
UniRef90:
UniRef90_O43683
UniRef50:
UniRef50_O43683
UniGene:
Hs.469649
CCDS:
CCDS62984.1,
CCDS33273.1,
CCDS62985.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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