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69865 A1cf

69865

A1cf

APOBEC1 complementation factor

protein-coding

Mus musculus

基因描述

Type Description
Definition APOBEC1 complementation factor

研究结论

Date Results Publications
2020-09-12 16:01:00 The RNA-Binding Protein A1CF Regulates Hepatic Fructose and Glycerol Metabolism via Alternative 31597092
2019-04-13 12:30:00 A1CF and RBM47 each function independently, yet interact in a tissue-specific manner, to regulate the activity and site selection of APOBEC1 dependent C-to-U RNA editing. 30309881
2018-01-27 10:59:00 Here, we show that partial loss of either APOBEC1 complementation factor (A1CF), the RNA-binding cofactor of APOBEC1 in RNA editing, or Argonaute 2 (AGO2), a key factor in the biogenesis of certain noncoding RNAs, modulates risk for TGCTs and testicular abnormalities in both parent-of-origin and conventional genetic manners. 27582469
2017-09-09 13:44:00 The observations demonstrate that A1CF does not act as the APOBEC1 complementation factor in vivo under normal physiological conditions and suggest new roles for A1CF, specifically within the male adult kidney. 28069890
2010-12-11 11:11:00 Data show that the importance of ACF for modulating ApoB was supported by the finding that knockdown of ACF reduced ApoB secretion. 20541607

名称对应

Type IDs
Synonymous 1810073H04Rik, 9130016M20Rik, ACF64, ACF65, ASP, Acf, MCM, MerCreMer, Tg(Myh6-cre/Esr1*)1Jmk, alpha-MHC-MerCreMer, alphaMHC-Cre-Mer-Cre, mer
Gene
UniProtKB-ID: A1CF_MOUSE
UniprotKB: Q5YD48
UniParc: UPI00001C621A, UPI0000434F26, UPI00001ECE6D
EMBL: AY566864, AY566862, AC117816, BC089622, AY566863, AC125019
Ensembl: ENSMUSG00000052595
KO: mmu:69865
Nucleutide sequences
EMBL-CDS: AAT74918.1, AAT74916.1, AAH89622.1, AAT74917.1
Ensembl_TRS: ENSMUST00000224304, ENSMUST00000075838, ENSMUST00000224564
Protein sequencees
Ensembl_PRO: ENSMUSP00000153542, ENSMUSP00000153465, ENSMUSP00000075235
RefSeq: NP_001352007.1, NP_001074543.1, XP_017173779.1
Others
UniRef100: UniRef100_Q5YD48
UniRef90: UniRef90_Q923K9
UniRef50: UniRef50_Q9NQ94
UniGene: Mm.87538
CCDS: CCDS89374.1, CCDS37959.1

全选

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