| Type | Description |
|---|---|
| Definition | phospholipase A2, group XIIB |
| Date | Results | Publications |
|---|---|---|
| 2020-05-30 12:03:00 | ERRgamma transcriptionally regulates the expression of PLA2G12B by binding to its promoter region. In Pla2g12b-null mice, ERRgamma fails to regulate hepatic VLDL-TG secretion and lipid droplets accumulate in the liver. ERRgamma is a novel regulator of hepatic VLDL-TG secretion, which is mediated through the action on PLA2G12B. | 30922124 |
| 2017-11-18 13:36:00 | FXR regulates serum triglyceride level in part through PLA2G12B. | 27471003 |
| 2013-05-04 10:47:00 | Low HDL Cholesterol Levels in strain Hlb218 Is Caused by a Mutation at amino acid position 129 in the third exon of Pla2g12b. | 22912808 |
| Type | IDs |
|---|---|
| Synonymous | 2010002E04Rik, Fksg71, Pla2g13, hlb218 |
| Gene |
UniProtKB-ID:
Q8VC81_MOUSE
UniprotKB:
Q8VC81
UniParc:
UPI0000021149
EMBL:
BC021592,
AY358033,
AC022699
Ensembl:
ENSMUSG00000009646
KO:
mmu:69836
|
| Nucleutide sequences |
EMBL-CDS:
AAQ92919.1,
AAH21592.1
Ensembl_TRS:
ENSMUST00000009790
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000009790
RefSeq:
XP_006514124.1,
NP_076019.2,
XP_006514125.1
|
| Others |
UniRef100:
UniRef100_Q8VC81
UniRef90:
UniRef90_Q99P27
UniRef50:
UniRef50_Q99P27
UniGene:
Mm.30268
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 30922124 |
FASEB J. Longhui Chen , Min Wu , Shengnan Zhang , Wenjuan Tan , Min Guan , Liqiang Feng , Chen Chen , Jun Tao , Ling Chen , Linbing Qu |
2019-07-01 | - |
| 27534441 |
Novel gene function revealed by mouse mutagenesis screens for models of age-related disease. Nat Commun Paul K Potter , Michael R Bowl , Prashanthini Jeyarajan , Laura Wisby , Andrew Blease , Michelle E Goldsworthy , Michelle M Simon , Simon Greenaway , Vincent Michel , Alun Barnard , Carlos Aguilar , Thomas Agnew , Gareth Banks , Andrew Blake , Lauren Chessum , Joanne Dorning , Sara Falcone , Laurence Goosey , Shelley Harris , Andy Haynes , Ines Heise , Rosie Hillier , Tertius Hough , Angela Hoslin , Marie Hutchison , Ruairidh King , Saumya Kumar , Heena V Lad , Gemma Law , Robert E MacLaren , Susan Morse , Thomas Nicol , Andrew Parker , Karen Pickford , Siddharth Sethi , Becky Starbuck , Femke Stelma , Michael Cheeseman , Sally H Cross , Russell G Foster , Ian J Jackson , Stuart N Peirson , Rajesh V Thakker , Tonia Vincent , Cheryl Scudamore , Sara Wells , Aziz El-Amraoui , Christine Petit , Abraham Acevedo-Arozena , Patrick M Nolan , Roger Cox , Anne-Marie Mallon , Steve D M Brown |
2016-08-18 | - |
| 27471003 |
Mol. Cell. Endocrinol. Qingli Liu , Meng Yang , Xuekun Fu , Renzhong Liu , Caijun Sun , Haobo Pan , Chi-Wai Wong , Min Guan |
2016-07-25 | - |
| 22912808 |
Pla2g12b and Hpn are genes identified by mouse ENU mutagenesis that affect HDL cholesterol. PLoS One Aleksandra Aljakna , Seungbum Choi , Holly Savage , Rachael Hageman Blair , Tongjun Gu , Karen L Svenson , Gary A Churchill , Matt Hibbs , Ron Korstanje |
2012-01-01 | - |
| 21873635 |
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas |
2011-09-01 | - |
| 21677750 |
A conditional knockout resource for the genome-wide study of mouse gene function. Nature William C Skarnes , Barry Rosen , Anthony P West , Manousos Koutsourakis , Wendy Bushell , Vivek Iyer , Alejandro O Mujica , Mark Thomas , Jennifer Harrow , Tony Cox , David Jackson , Jessica Severin , Patrick Biggs , Jun Fu , Michael Nefedov , Pieter J de Jong , A Francis Stewart , Allan Bradley |
2011-06-15 | - |
| 21267068 |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. Graciana Diez-Roux , Sandro Banfi , Marc Sultan , Lars Geffers , Santosh Anand , David Rozado , Alon Magen , Elena Canidio , Massimiliano Pagani , Ivana Peluso , Nathalie Lin-Marq , Muriel Koch , Marchesa Bilio , Immacolata Cantiello , Roberta Verde , Cristian De Masi , Salvatore A Bianchi , Juliette Cicchini , Elodie Perroud , Shprese Mehmeti , Emilie Dagand , Sabine Schrinner , Asja Nürnberger , Katja Schmidt , Katja Metz , Christina Zwingmann , Norbert Brieske , Cindy Springer , Ana Martinez Hernandez , Sarah Herzog , Frauke Grabbe , Cornelia Sieverding , Barbara Fischer , Kathrin Schrader , Maren Brockmeyer , Sarah Dettmer , Christin Helbig , Violaine Alunni , Marie-Annick Battaini , Carole Mura , Charlotte N Henrichsen , Raquel Garcia-Lopez , Diego Echevarria , Eduardo Puelles , Elena Garcia-Calero , Stefan Kruse , Markus Uhr , Christine Kauck , Guangjie Feng , Nestor Milyaev , Chuang Kee Ong , Lalit Kumar , MeiSze Lam , Colin A Semple , Attila Gyenesei , Stefan Mundlos , Uwe Radelof , Hans Lehrach , Paolo Sarmientos , Alexandre Reymond , Duncan R Davidson , Pascal Dollé , Stylianos E Antonarakis , Marie-Laure Yaspo , Salvador Martinez , Richard A Baldock , Gregor Eichele , Andrea Ballabio |
2011-01-18 | - |
| 17683524 |
BMC Dev. Biol. Juan Hou , Anita M Charters , Sam C Lee , Yongjun Zhao , Mona K Wu , Steven J M Jones , Marco A Marra , Pamela A Hoodless |
2007-01-01 |
Lgals2,
Apoc2,
Arg1,
Cdx1,
Cyp26a1,
Gabpb1,
Hoxb6,
Otx2,
Prrx2,
Spink1,
Tbx1,
Usp22,
Pyy,
Trap1a,
Trh,
Phlda2,
Ttr,
Habp2,
Mogat2,
Prtg,
Fndc3c1,
Cldn9,
Tdh,
Cubn,
Nepn,
1700011H14Rik,
Pla2g12b,
Spp2,
Cpn1
|
| 16141072 |
The transcriptional landscape of the mammalian genome. Science P Carninci , T Kasukawa , S Katayama , J Gough , M C Frith , N Maeda , R Oyama , T Ravasi , B Lenhard , C Wells , R Kodzius , K Shimokawa , V B Bajic , S E Brenner , S Batalov , A R R Forrest , M Zavolan , M J Davis , L G Wilming , V Aidinis , J E Allen , A Ambesi-Impiombato , R Apweiler , R N Aturaliya , T L Bailey , M Bansal , L Baxter , K W Beisel , T Bersano , H Bono , A M Chalk , K P Chiu , V Choudhary , A Christoffels , D R Clutterbuck , M L Crowe , E Dalla , B P Dalrymple , B de Bono , G Della Gatta , D di Bernardo , T Down , P Engstrom , M Fagiolini , G Faulkner , C F Fletcher , T Fukushima , M Furuno , S Futaki , M Gariboldi , P Georgii-Hemming , T R Gingeras , T Gojobori , R E Green , S Gustincich , M Harbers , Y Hayashi , T K Hensch , N Hirokawa , D Hill , L Huminiecki , M Iacono , K Ikeo , A Iwama , T Ishikawa , M Jakt , A Kanapin , M Katoh , Y Kawasawa , J Kelso , H Kitamura , H Kitano , G Kollias , S P T Krishnan , A Kruger , S K Kummerfeld , I V Kurochkin , L F Lareau , D Lazarevic , L Lipovich , J Liu , S Liuni , S McWilliam , M Madan Babu , M Madera , L Marchionni , H Matsuda , S Matsuzawa , H Miki , F Mignone , S Miyake , K Morris , S Mottagui-Tabar , N Mulder , N Nakano , H Nakauchi , P Ng , R Nilsson , S Nishiguchi , S Nishikawa , F Nori , O Ohara , Y Okazaki , V Orlando , K C Pang , W J Pavan , G Pavesi , G Pesole , N Petrovsky , S Piazza , J Reed , J F Reid , B Z Ring , M Ringwald , B Rost , Y Ruan , S L Salzberg , A Sandelin , C Schneider , C Schönbach , K Sekiguchi , C A M Semple , S Seno , L Sessa , Y Sheng , Y Shibata , H Shimada , K Shimada , D Silva , B Sinclair , S Sperling , E Stupka , K Sugiura , R Sultana , Y Takenaka , K Taki , K Tammoja , S L Tan , S Tang , M S Taylor , J Tegner , S A Teichmann , H R Ueda , E van Nimwegen , R Verardo , C L Wei , K Yagi , H Yamanishi , E Zabarovsky , S Zhu , A Zimmer , W Hide , C Bult , S M Grimmond , R D Teasdale , E T Liu , V Brusic , J Quackenbush , C Wahlestedt , J S Mattick , D A Hume , C Kai , D Sasaki , Y Tomaru , S Fukuda , M Kanamori-Katayama , M Suzuki , J Aoki , T Arakawa , J Iida , K Imamura , M Itoh , T Kato , H Kawaji , N Kawagashira , T Kawashima , M Kojima , S Kondo , H Konno , K Nakano , N Ninomiya , T Nishio , M Okada , C Plessy , K Shibata , T Shiraki , S Suzuki , M Tagami , K Waki , A Watahiki , Y Okamura-Oho , H Suzuki , J Kawai , Y Hayashizaki , FANTOM Consortium , RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group) |
2005-09-02 | - |
| 16141073 |
Antisense transcription in the mammalian transcriptome. Science S Katayama , Y Tomaru , T Kasukawa , K Waki , M Nakanishi , M Nakamura , H Nishida , C C Yap , M Suzuki , J Kawai , H Suzuki , P Carninci , Y Hayashizaki , C Wells , M Frith , T Ravasi , K C Pang , J Hallinan , J Mattick , D A Hume , L Lipovich , S Batalov , P G Engström , Y Mizuno , M A Faghihi , A Sandelin , A M Chalk , S Mottagui-Tabar , Z Liang , B Lenhard , C Wahlestedt , RIKEN Genome Exploration Research Group , Genome Science Group (Genome Network Project Core Group) , FANTOM Consortium |
2005-09-02 |
Gm14018,
Gm14964,
F630206G17Rik,
Oog3,
Notumos,
Ldlrap1,
Mdn1,
Pydc3,
9330171B17Rik,
Mfap1b,
Tmsb15b2,
Gm12802,
E430020m11rik,
Gm11335,
Gm15772,
Gm17762,
A930017K11Rik,
LOC100036513,
Gata5os,
Umad1,
Gm16982,
Gm9887,
Gm9872,
LOC100036530,
Gm9934,
Gm9913,
Gm11149,
BC028777,
Gm13999,
LOC100036540,
Gm9744,
Gm9983,
D630002J18Rik,
Gm16525,
Gm11696,
Dnajc3,
9430060I03Rik,
Gm12359,
4921516A02Rik,
Fam129c,
Gm10589,
Rsph3b,
Rnaset2a,
5430403G19Rik,
D030047H15Rik,
Gm13274,
B930046K06Rik,
Gm10862,
Gm10792,
Gm10802,
Gm10532,
G730003C15Rik,
Runx2os1,
Gm15612,
Gm10856,
Gm10857,
Gm10685,
Gm10803,
Gm10723,
F630028O10Rik,
Gm10836,
Gm10405,
Gm10513,
Gm10609,
F630201L12Rik,
4932427H20Rik,
Zfp389,
Gm10763,
Gm10062,
Gm10714,
Gm10531,
Gm10876,
Gm10750,
Gm10433,
Gm10837,
Gm10647,
Gm10648,
Gm10650,
Gm10610,
F830115B05Rik,
Gm10473,
Gm10614,
Gm10286,
G730046D07Rik,
Gm10287,
Gm10785,
Gm10183,
Gm10512,
1700061E17Rik,
Gm44113,
Gm10579,
Gm10741,
Gm10827,
Gm10522,
Gm10536,
Gm15998,
Faddos,
D130050E23Rik,
Gm10735
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
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| 排名 | 研究人员 | 文献 |
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