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69716 Trip13

69716

Trip13

thyroid hormone receptor interactor 13

protein-coding

Mus musculus

基因描述

Type Description
Definition thyroid hormone receptor interactor 13

研究结论

Date Results Publications
2018-11-17 11:51:00 In all, these studies suggest that insufficient TRIP13 increased the susceptibility of damaged tubular epithelial cells to progress towards apoptotic cell death. 28256593
2018-03-10 10:55:00 TRIP13 ubiquitinates and degrades the checkpoint surveillance protein MAD2 via activating Akt signaling pathway, leading to weakened checkpoint surveillance and consequent tumorigenic aneuploidy and drug resistance in MM. 28157697
2015-12-26 12:10:00 TRIP13-deficient spermatocytes also progress to an H1t-positive stage if ATM activity is attenuated by hypomorphic mutations in Mre11 or Nbs1 or by elimination of the ATM-effector kinase CHK2 25768017
2015-11-07 10:09:00 TRIP13 promotes error-prone non-homologous end joining and induces chemoresistance in head and neck cancer. 25078033
2011-01-01 10:54:00 TRIP13 is required for recombination and normal higher-order chromosome structure during meiosis. 20711356

名称对应

Type IDs
Synonymous 2410002G23Rik, D13Ertd328e
Gene
UniProtKB-ID: PCH2_MOUSE
UniprotKB: Q3UA06
UniParc: UPI0000021C4F, UPI00004CAE39
EMBL: BC126946, AK142463, BC023834, AK151568, CT010471, AK010336, CH466563, AK146877
Ensembl: ENSMUSG00000021569
KO: mmu:69716
Nucleutide sequences
EMBL-CDS: BAE30510.1, AAI26947.1, BAE27499.1, EDL37076.1, BAB26861.1, BAE25076.1, AAH23834.1
Ensembl_TRS: ENSMUST00000022053
Protein sequencees
Ensembl_PRO: ENSMUSP00000022053
RefSeq: NP_081458.1
Others
UniRef100: UniRef100_Q3UA06
UniRef90: UniRef90_Q3UA06
UniRef50: UniRef50_Q3UA06
UniGene: Mm.275095
CCDS: CCDS26637.1

全选

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研究热度

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