| Type | Description |
|---|---|
| Definition | hemojuvelin BMP co-receptor |
| Date | Results | Publications |
|---|---|---|
| 2021-01-09 13:30:00 | The functional role of hemojuvelin in acute ischemic stroke. | 31307288 |
| 2020-06-27 11:40:00 | Hjv was significantly downregulated in the muscles of mdx mice as well as in those of aged mice. Overexpression of Hjv rescued dystrophic and age-related muscle wasting. Mechanistically, loss of Hjv promoted activation of Smad3 signalling induced by TGF-beta1, whereas Hjv overexpression inhibited TGF-beta1/Smad3 signalling by directly interacting with TbetaRII on the muscle membrane. | 30884219 |
| 2019-07-20 11:50:00 | We conclude that Hjv is required for inflammatory induction of hepcidin and controls the acute hypoferremic response | 30213871 |
| 2018-01-27 11:42:00 | Anti-hemojuvelin antibody corrects anemia caused by inappropriately high hepcidin levels | 26944476 |
| 2017-12-16 11:03:00 | These data suggest that, in Hjv(-/-) females, Bmp6 can provide a signal adequate to maintain hepcidin to a level sufficient to avoid extrahepatic iron loading. | 29021231 |
| Type | IDs |
|---|---|
| Synonymous | 2310035L15Rik, 5230400G09Rik, AI414844, AI789733, DL-M, Hfe2, Rgmc, hemojuvelin |
| Gene |
UniProtKB-ID:
RGMC_MOUSE
UniprotKB:
Q7TQ32
UniParc:
UPI0000026E59,
UPI00001ADD9A
EMBL:
AJ557515,
AK009636,
AK014082,
BC022603
Ensembl:
ENSMUSG00000038403
KO:
mmu:69585
|
| Nucleutide sequences |
EMBL-CDS:
BAB26407.1,
AAH22603.1,
CAD89720.1,
BAC25423.1
Ensembl_TRS:
ENSMUST00000049208
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000046659
RefSeq:
NP_081402.3,
XP_036019189.1,
XP_006502100.1
|
| Others |
UniRef100:
UniRef100_Q7TQ32
UniRef90:
UniRef90_Q7TQ32
UniRef50:
UniRef50_Q7TQ32
UniGene:
Mm.171314
CCDS:
CCDS51003.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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