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69581 Rhou

69581

Rhou

ras homolog family member U

protein-coding

Mus musculus

基因描述

Type Description
Definition ras homolog family member U

研究结论

Date Results Publications
2020-02-08 12:16:00 Coupling our top hit with gain/loss-of-function genetics, interactome proteomics and tissue imaging, the authors show that RHOU, an atypical Rho, governs the cytoskeletal-junction dynamics that establish columnar shape and planar cell polarity in epidermal progenitors. 31556874
2019-08-03 12:11:00 Loss of RhoU function in the mouse gut epithelium increases RhoA activity and the level of phosphorylated myosin light chain-2. Rhou knockdown in the mouse gut causes cell hyperplasia. 30834544
2011-12-03 10:26:00 Rhou activity maintains the epithelial architecture of the endoderm progenitors, and its downregulation accompanies the transition of the columnar epithelium in the embryonic foregut to a multilayered cell sheet during organ formation. 21903671
2010-01-21 00:00:00 Wrch1 collaborates with FAK2 and Src in regulating cytoskeletal dynamics. 18086875
2010-01-21 00:00:00 G28K was differentially expressed in the small intestines; interstitial cells of Cajal within the small intestine expressed mRNA for G28K; downregulated in the jejunum of W/W V mice. 14731133

名称对应

Type IDs
Synonymous 2310026M05Rik, AI182090, Arhu, CDC42L1, G28K, WRCH-1, WRCH1, mG28K
Gene
UniProtKB-ID: RHOU_MOUSE
UniprotKB: Q9EQT3
UniParc: UPI0000027535
EMBL: AB051827, AF378088
Ensembl: ENSMUSG00000039960
KO: mmu:69581
Nucleutide sequences
EMBL-CDS: AAK83341.1, BAB18639.1
Ensembl_TRS: ENSMUST00000045487
Protein sequencees
Ensembl_PRO: ENSMUSP00000038915
RefSeq: NP_598716.1
Others
UniRef100: UniRef100_Q9EQT3
UniRef90: UniRef90_Q9EQT3
UniRef50: UniRef50_Q9EQT3
UniGene: Mm.168257
CCDS: CCDS22762.1

全选

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