| Type | Description |
|---|---|
| Definition | MAX dimerization protein MLX |
| Date | Results | Publications |
|---|---|---|
| 2020-10-24 14:09:00 | The MNT transcription factor autoregulates its expression and supports proliferation in MYC-associated factor X (MAX)-deficient cells. | 31919096 |
| 2019-09-21 11:08:00 | MLX-Q139R mutation plays a crucial role in the pathogenesis of Takayasu arteritis through promoting inflammasome formation. | 30354298 |
| 2015-08-29 10:53:00 | MYC is part of a network of bHLHLZ proteins centered on the MYC heterodimeric partner MAX and its counterpart, the MAX-like protein MLX. | 24857747 |
| 2015-04-25 10:21:00 | Knockdown of MondoA, or its dimerization partner Mlx, blocks Myc-induced reprogramming of multiple metabolic pathways, resulting in apoptosis | 25640402 |
| 2010-01-21 00:00:00 | Mlx is an obligatory partner of ChREBP in regulating lipogenic enzyme genes in liver. | 15664996 |
| Type | IDs |
|---|---|
| Synonymous | MAD7, MXD7, TCFL4, TF4, bHLHd13 |
| Gene |
UniProtKB-ID:
MLX_HUMAN
UniprotKB:
Q9UH92
UniParc:
UPI000012F237,
UPI000002AE24,
UPI000002AE23
EMBL:
AK000150,
BC010689,
AF203978,
AF213667,
AK290258,
AK314378,
AF213666,
AK315432,
BT009812,
AF213668
Ensembl:
ENSG00000108788
KO:
hsa:6945
|
| Nucleutide sequences |
EMBL-CDS:
AAH10689.1,
AAG40147.1,
BAG37005.1,
AAG40145.1,
BAF82947.1,
BAG37820.1,
AAP88814.1,
AAG40146.1,
BAA90977.1,
AAF14638.1
Ensembl_TRS:
ENST00000246912,
ENST00000435881,
ENST00000346833
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000320913,
ENSP00000246912,
ENSP00000416627
RefSeq:
NP_937848.1,
NP_733752.1,
NP_937847.1
|
| Others |
UniRef100:
UniRef100_Q9UH92
UniRef90:
UniRef90_Q9UH92
UniRef50:
UniRef50_Q9UH92
UniGene:
Hs.383019,
Hs.714749
CCDS:
CCDS45687.1,
CCDS11430.1,
CCDS42341.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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