例如："NBL1", "4681", "drought"
收藏
6938 TCF12

6938

TCF12

transcription factor 12

protein-coding

Homo sapiens

基因描述

Type Description
Definition transcription factor 12

研究结论

Date Results Publications
2020-08-15 19:03:00 High expression of TCF12 contributes to gastric cancer development via being target regulated by miR-183 and activating PI3K/AKT pathway. 30982999
2020-06-06 12:17:00 Study demonstrates that TCF12 is a direct target of miR26a, and upregulation of miR26a resulted in TCF12 inhibition in epithelial ovarian cancer (OC) cells. Furthermore, the proliferation, migration and invasion were inhibited and apoptosis was induced by miR26a upregulation in OC cells. These results indicated that miR26a may act as a tumor suppressor in OC, and TCF12 targeting by miR26a. 31789414
2020-02-29 12:15:00 The results suggest that TCF12 is a poor prognostic factor of ovarian cancer 31311684
2019-03-16 10:12:00 directly interacts with AML1-ETO, confers new DNA-binding capacity to the AML1-ETO-containing transcription factor complex, and is essential for leukemogenesis 30593567
2019-02-02 10:51:00 Pathogenic or likely pathogenic variants in non-FGFR genes were identified in 43 individuals, with diagnostic yields of 14% and 15% in retrospective and prospective cohorts, respectively. Variants were identified most frequently in TCF12 (N = 22) and EFNB1 (N = 8), typically in individuals with nonsyndromic coronal craniosynostosis or TWIST1-negative clinically suspected Saethre-Chotzen syndrome. 29215649

名称对应

Type IDs
Synonymous CRS3, HEB, HTF4, HsT17266, TCF-12, bHLHb20, p64
Gene
UniProtKB-ID: HTF4_HUMAN, F5GY10_HUMAN, A0A024R5T1_HUMAN, A0A024R5Z0_HUMAN
UniprotKB: Q99081, F5GY10, A0A024R5T1, A0A024R5Z0
UniParc: UPI00001FE54C, UPI000018CEA6, UPI000003B45E, UPI0002064EC9, UPI00017A87DE
EMBL: M83233, AK304007, BX537967, AC090532, KF456057, AL831981, BC050556, BK001049, AC016525, AC010999, M65209, M80627, CH471082, AC090511
Ensembl: ENSG00000140262
KO: hsa:6938
Nucleutide sequences
EMBL-CDS: AAB62389.1, CAD89914.1, AAH50556.1, DAA01129.1, AAC37571.1, BAG64923.1, AAA58632.1, EAW77512.1, CAD97931.1, EAW77516.1, EAW77513.1, EAW77517.1, EAW77514.1
Gene_ORFName: hCG_40686, hCG_40686
Ensembl_TRS: ENST00000438423, ENST00000267811, ENST00000343827, ENST00000333725, ENST00000537840, ENST00000557843, ENST00000543579
Protein sequencees
Ensembl_PRO: ENSP00000453737, ENSP00000342459, ENSP00000331057, ENSP00000388940, ENSP00000444696, ENSP00000267811, ENSP00000440017
RefSeq: XP_016878009.1, XP_011520263.1, NP_001309091.1, NP_003196.1, NP_001309083.1, XP_011520269.1, NP_001293148.1, NP_001309094.1, XP_011520262.1, NP_001309081.1, XP_011520267.1, NP_001293149.1, NP_996920.1, XP_011520271.1, XP_011520265.1, NP_001309093.1, NP_996919.1, NP_001309080.1, XP_011520264.1, XP_011520261.1, XP_011520268.1, NP_996921.1, NP_001309087.1, NP_001309085.1, NP_001309088.1, NP_996923.1, NP_001309090.1, NP_001309086.1
Others
UniRef100: UniRef100_Q99081, UniRef100_A0A024R5Z0, UniRef100_F5GY10
UniRef90: UniRef90_Q99081, UniRef90_A0A2I3HCX3
UniRef50: UniRef50_Q99081, UniRef50_Q60420
UniGene: Hs.511504
CCDS: CCDS76761.1, CCDS42042.1, CCDS10159.1, CCDS10160.1

全选

{{proteinIndex+1}}		 mRNA Protein UniprotKB Description
Refseq {{protein.nucleotideVersion}}

Ensembl: {{protein.nucleotideEnsembl}}

{{protein.proteinVersion}}

Ensembl: {{protein.proteinEnsembl}}

{{uniprot}}
Definition: {{{protein.definition}}}

Transcript Veriant:{{protein.transcriptVeriant}}

Status: {{protein.status}}
Location ( {{protein.positionStart}}..{{protein.positionEnd}} )

暂无数据

研究热度

热点单位
排名 科研单位 文献
{{affIndex+1}}

{{aff.value}}

 {{aff.size}}

目前还没有研究热点单位

热点人员
排名 研究人员 文献
{{authorIndex+1}}

{{author.value}}

 {{author.size}}

目前还没有研究热点人员

© 2017 biocloud.net版权所有 ICP证：京10042835号