| Type | Description |
|---|---|
| Definition | glutaredoxin 2 (thioltransferase) |
| Date | Results | Publications |
|---|---|---|
| 2021-04-17 13:17:00 | Glutaredoxin-2 and Sirtuin-3 deficiencies impair cardiac mitochondrial energetics but their effects are not additive. | 33002579 |
| 2020-09-19 12:49:00 | The deleting the Grx2 gene can protect from diet-induced weight gain and the development of obesity-related disorders. | 31317766 |
| 2018-10-13 11:49:00 | ur results demonstrate that the GRX2-mediated regulation of O2(*-)/H2O2 release through the S-glutathionylation of mitochondrial proteins may play an integral role in controlling cellular signaling | 29274570 |
| 2018-07-21 12:10:00 | Grx2 absence impairs mitochondrial fusion, ultrastructure and energetics in primary cardiomyocytes and cardiac tissue. | 29101900 |
| 2018-04-14 10:41:00 | Study shows that Grx2 detoxifies *NO in mature oligodendrocytes and oligodendroglial precursor cellsvia the formation of dinitrosyl-iron-complexes, inhibiting the formation of harmful peroxynitrite and reducing subsequent oligodendroglial damage. Findings link inorganic biochemistry to neuroinflammation and identify glutaredoxin 2 as a protective factor against neuroinflammation-mediated myelin damage. | 28618115 |
| Type | IDs |
|---|---|
| Synonymous | 1700010P22Rik, AI645710, Grx2 |
| Gene |
UniProtKB-ID:
GLRX2_MOUSE,
Q3UQ95_MOUSE,
A2A5W4_MOUSE
UniprotKB:
Q923X4,
Q3UQ95,
A2A5W4
UniParc:
UPI0000021593,
UPI0000028E7D
EMBL:
AF380337,
BC132033,
AF276918,
AK142654,
BC145304,
AK005853,
BC132031
Ensembl:
ENSMUSG00000018196
KO:
mmu:69367
|
| Nucleutide sequences |
EMBL-CDS:
AAK85319.1,
BAB24276.1,
AAF86465.1,
BAE25147.1,
AAI45305.1,
AAI32034.1,
AAI32032.1
Ensembl_TRS:
ENSMUST00000185362,
ENSMUST00000111957,
ENSMUST00000129653,
ENSMUST00000145969
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000141022,
ENSMUSP00000107588,
ENSMUSP00000121010,
ENSMUSP00000121665
RefSeq:
NP_075994.2,
XP_006529919.1,
NP_001033681.1,
NP_001033682.1,
NP_001033683.1,
XP_011246370.1,
XP_006529918.2
|
| Others |
UniRef100:
UniRef100_Q923X4
UniRef90:
UniRef90_Q923X4
UniRef50:
UniRef50_Q923X4
UniGene:
Mm.272727
CCDS:
CCDS15344.1,
CCDS15343.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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