| Type | Description |
|---|---|
| Definition | PARK2 co-regulated |
| Date | Results | Publications |
|---|---|---|
| 2019-10-12 10:20:00 | Results show that aged single knockout Pacrg mouse and double knockout parkin-Pacrg mouse do not show behavioral or neuropathological deficits of the dopaminergic system. Collectively, these studies suggest that gene mediated deficiency in the mouse may alter pathways common to human pathogenesis but for as yet unknown reasons do not cause a pronounced Parkinson disease-like phenotype. | 29760428 |
| 2015-04-25 12:17:00 | Studies demonstrate that MEIG1/PACRG forms a complex in the manchette and that this complex is necessary to transport cargos, such as to build the sperm flagella. | 25715396 |
| 2010-09-20 11:28:00 | Pacrg is required for motile cilia function and may be involved in the pathogenesis of hydrocephalus. | 20106870 |
| 2010-01-21 12:47:00 | Findings reveal a critical role for the MEIG1/PARCG partnership in manchette structure and function and the control of spermiogenesis. | 19805151 |
| 2010-01-21 00:00:00 | The quaking mutation is a deletion of approximately 1.17 Mb of mouse chromosome 17, resulting in the deletion of the entire promoter and first five coding exons of PRKN. The recently described Parkin Co-Regulated Gene (PACRG) is completely deleted. | 14743368 |
| Type | IDs |
|---|---|
| Synonymous | 1700008H23Rik |
| Gene |
UniProtKB-ID:
PACRG_MOUSE,
Q0VB91_MOUSE,
Q3UXK4_MOUSE
UniprotKB:
Q9DAK2,
Q0VB91,
Q3UXK4
UniParc:
UPI0000028096,
UPI00005ABB9E
EMBL:
AC109609,
AK005771,
AK135510,
BC120740,
AF549257
Ensembl:
ENSMUSG00000037196
KO:
mmu:69310
|
| Nucleutide sequences |
EMBL-CDS:
AAP94052.1,
AAO16245.1,
BAB24230.1,
AAI20741.1,
BAE22559.1
Ensembl_TRS:
ENSMUST00000041463
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000044376
RefSeq:
XP_006523416.1,
NP_081308.1
|
| Others |
UniRef100:
UniRef100_Q9DAK2,
UniRef100_Q3UXK4
UniRef90:
UniRef90_Q9DAK2
UniRef50:
UniRef50_Q9DAK2
UniGene:
Mm.18889
CCDS:
CCDS28388.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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