| Type | Description |
|---|---|
| Definition | lysine (K)-specific methyltransferase 2E |
| Date | Results | Publications |
|---|---|---|
| 2018-12-29 11:19:00 | MLL5 has a role in suppressing antiviral innate immune response by facilitating STUB1-mediated RIG-I degradation | 29593341 |
| 2018-05-21 11:26:00 | toxic reactive oxygen species levels in Mll5(-/-) mice are critically dependent on type 1 interferon (IFN-1) signaling, which triggers mitochondrial accumulation of full-length Bid.[IFN-1] | 27641306 |
| 2010-01-21 00:00:00 | MLL5 plays an integral role in novel chromatin regulatory mechanisms that suppress inappropriate expression of S-phase-promoting genes and maintain expression of determination genes in quiescent cells. | 19264965 |
| 2010-01-21 00:00:00 | MLL5 is a key regulator of normal hematopoiesis | 18854576 |
| 2010-01-21 00:00:00 | findings establish several nonredundant functions for Mll5, including an essential role in regulating proliferation and functional integrity of hematopoietic stem/progenitor cells | 18952892 |
| Type | IDs |
|---|---|
| Synonymous | 1810033J14Rik, 9530077A04Rik, D230038D11Rik, Mll5, NKp44L |
| Gene |
UniProtKB-ID:
KMT2E_MOUSE
UniprotKB:
Q3UG20
UniParc:
UPI0001750282,
UPI0000603B12
EMBL:
AK148169,
BC089356,
AK160519,
BC036286,
AK021284,
BC064079,
AC122022,
BC103801,
AK007682,
AK035078
Ensembl:
ENSMUSG00000029004
KO:
mmu:69188
|
| Nucleutide sequences |
EMBL-CDS:
AAH36286.1,
AAH89356.1,
BAB25186.1,
BAE35839.1,
BAE28389.1,
AAH64079.1,
BAE43262.1,
BAC28936.2,
AAI03802.1
Ensembl_TRS:
ENSMUST00000094962,
ENSMUST00000115128
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000110781,
ENSMUSP00000092569
RefSeq:
XP_017176579.1,
XP_036021362.1,
XP_006535870.1,
XP_006535868.1,
NP_081260.1,
XP_006535869.1
|
| Others |
UniRef100:
UniRef100_Q3UG20
UniRef90:
UniRef90_Q3UG20
UniRef50:
UniRef50_Q8IZD2
UniGene:
Mm.205190,
Mm.403814
CCDS:
CCDS51430.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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