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6917 TCEA1

6917

TCEA1

transcription elongation factor A1

protein-coding

Homo sapiens

基因描述

Type Description
Definition transcription elongation factor A1

研究结论

Date Results Publications
2020-02-22 12:28:00 A mutant form of TFIIS increased RNAPII pausing and backtracking results in R-loop formation and genome instability. 31519522
2011-08-06 11:13:00 RNF20, presumably via H2Bub, selectively represses oncogenic genes by interfering with chromatin recruitment of TFIIS, a factor capable of relieving stalled RNA polymerase II. RNF20 inhibits the interaction between TFIIS and the PAF1 complex. 21596312
2011-03-19 11:43:00 a role for TFIIS in transcription recovery and re-establishment of the balance between hypo- and hyper-phosphorylated RNAPII after DNA damage repair 20729154
2011-03-05 10:42:00 Results indicate that TFIIS is not limiting for the repair of transcription-blocking DNA lesions and thus the present work does not support a role for TFIIS in TC-NER. 21070792
2010-01-21 00:00:00 PLAG1 protein is overexpressed in epithelial, myoepithelial, and mesenchymal-like tumor cells in tumors with fusions to CHCHD7 and TCEA1. 16736500

名称对应

Type IDs
Synonymous GTF2S, SII, TCEA, TF2S, TFIIS
Gene
UniProtKB-ID: TCEA1_HUMAN, B7Z4W0_HUMAN, A0A384MTX4_HUMAN
UniprotKB: P23193, B7Z4W0, A0A384MTX4
UniParc: UPI0000136ABE, UPI0001914FF4, UPI000002B4ED
EMBL: BT019995, AK297957, GQ900953, X57198, BC072460, X73534, X62585, M81601, CR542221, AK290454, AC100821
Ensembl: ENSG00000187735
KO: hsa:6917
Nucleutide sequences
EMBL-CDS: AAH72460.1, AAA61138.1, BAF83143.1, AAV38798.1, CAA51940.1, CAA44470.1, CAG47017.1, CAA40484.1, BAH12696.1, ADO22470.1
Ensembl_TRS: ENST00000396401, ENST00000521604
Protein sequencees
Ensembl_PRO: ENSP00000395483, ENSP00000428426
RefSeq: NP_006747.1, XP_011515880.1, XP_006716530.1, NP_958845.1
Others
UniRef100: UniRef100_B7Z4W0, UniRef100_P23193
UniRef90: UniRef90_A0A1W2PPZ5, UniRef90_P23193
UniRef50: UniRef50_P10711, UniRef50_P23193
UniGene: Hs.491745
CCDS: CCDS47857.1, CCDS47858.1

全选

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