| Type | Description |
|---|---|
| Definition | thromboxane A synthase 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-09-12 15:59:00 | Thromboxane A synthase 1 gene expression and promotor haplotypes are associated with risk of large artery-atherosclerosis stroke in Iranian population. | 31026093 |
| 2019-03-09 10:19:00 | The available theoretical and experimental data have elucidated the very important role of the thromboxane A2 - thromboxane A synthase - thromboxane A2 receptor axis in the pathogenesis of thrombotic diseases. Systematic studies are required to verify genetic markers in patients at high cardiovascular risk, in order to achieve more effective diagnostics and treatment. [review] | 30039765 |
| 2017-12-16 11:00:00 | RS41708TT is not only independent risk factor for symptomatic carotid artery or intracranial arterial stenosis, but is also independent risk predictor for neurologic deterioration in ischemic stroke patients. | 28108096 |
| 2017-12-02 11:10:00 | Sequencing revealed two novel biallelic variants of unknown significance within the thromboxane A synthase gene, TBXAS1 (c.266T > C; c.989T > C), bioinformatically predicted to disrupt the protein. TBXAS1 mutations result in Ghosal hematodiaphyseal dysplasia (OMIM 231095), the autosomal recessive syndrome associated with abnormal bone structure and BMF. | 28868793 |
| 2017-10-07 12:07:00 | TXAS1 rs2267679TT and rs41708TT genotypes are associated with carotid plaque vulnerability, platelet activation and TXA2 levels in ischemic stroke patients. | 28704403 |
| Type | IDs |
|---|---|
| Synonymous | BDPLT14, CYP5, CYP5A1, GHOSAL, THAS, TS, TXAS, TXS |
| Gene |
UniProtKB-ID:
THAS_HUMAN,
Q53F23_HUMAN,
B4DVP1_HUMAN,
A0A0A0MSK3_HUMAN,
A0A0C4DH47_HUMAN
UniprotKB:
P24557,
Q53F23,
B4DVP1,
A0A0A0MSK3,
A0A0C4DH47
UniParc:
UPI0000EE4047,
UPI000007035B,
UPI0000074740,
UPI0001AE4FCB,
UPI00017A7CEE,
UPI00042DB676,
UPI00042DB677,
UPI00017A722C
EMBL:
L36079,
AF233623,
L36076,
KF573672,
L36081,
CH471070,
AF233621,
AC004914,
L36083,
AK223466,
BC014117,
AF233618,
M80646,
M74055,
AF233616,
AF233624,
AF233619,
L36082,
AK301164,
L36080,
AF233620,
L36077,
L36078,
AF233617,
M80647,
AK296069,
KF459643,
AF233622,
L36075,
L36085,
AC004961,
L36084,
D34625,
AF233625,
BC041157,
AF233615,
AC006021
Ensembl:
ENSG00000059377
KO:
hsa:6916
|
| Nucleutide sequences |
EMBL-CDS:
AAA60618.1,
AAA60617.1,
AAA36742.1,
AAF99275.1,
BAG58828.1,
AAH41157.1,
AAF99277.1,
AAF99270.1,
EAW83934.1,
AAF99272.1,
AAF99271.1,
AAH14117.1,
AAF99276.1,
AAF99274.1,
AAF99269.1,
AAC01761.1,
AAF99273.1,
AAF99278.1,
AAF99279.1,
BAA07011.1,
EAW83935.1,
BAD97186.1,
BAG62753.1,
EAW83936.1
Gene_ORFName:
hCG_14925,
hCG_14925
Ensembl_TRS:
ENST00000458722,
ENST00000425687,
ENST00000448866,
ENST00000411653,
ENST00000336425,
ENST00000650822,
ENST00000652056,
ENST00000416849
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000338087,
ENSP00000411274,
ENSP00000411326,
ENSP00000402536,
ENSP00000388736,
ENSP00000498517,
ENSP00000498271,
ENSP00000389414
RefSeq:
NP_001300957.1,
XP_024302669.1,
NP_001353466.1,
NP_112246.3,
NP_001159725.2,
XP_011514846.1,
NP_001353467.1,
XP_016868059.1,
NP_001159726.1,
XP_016868061.1,
XP_016868060.1,
NP_001124438.2,
NP_001052.3
|
| Others |
UniRef100:
UniRef100_B4DVP1,
UniRef100_P24557,
UniRef100_A0A0A0MSK3,
UniRef100_A0A0C4DH47
UniRef90:
UniRef90_B4DVP1,
UniRef90_P24557,
UniRef90_A0A0A0MSK3
UniRef50:
UniRef50_F6SZ84,
UniRef50_P24557
UniGene:
Hs.520757
CCDS:
CCDS5855.1,
CCDS55174.1,
CCDS5856.1,
CCDS55175.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员