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68949 Zfas1

68949

Zfas1

zinc finger, NFX1-type containing 1, antisense RNA 1

ncRNA

Mus musculus

基因描述

Type Description
Definition zinc finger, NFX1-type containing 1, antisense RNA 1

研究结论

Date Results Publications
2020-12-12 13:29:00 SP1-induced ZFAS1 aggravates sepsis-induced cardiac dysfunction via miR-590-3p/NLRP3-mediated autophagy and pyroptosis. 33002446
2020-09-05 13:58:00 lncRNA-ZFAS1 induces mitochondria-mediated apoptosis by causing cytosolic Ca(2+) overload in myocardial infarction mice model. 31819041
2019-09-21 12:09:00 ZFAS1 expression was increased in cytoplasm and sarcoplasmic reticulum in a mouse model of myocardial infarction and a cellular model of hypoxia. ZFAS1 knockdown or overexpression impaired heart function. ZFAS1 deleteriously altered the Ca(2+) transient leading to intracellular Ca(2+) overload. It binds, limits, and represses SERCA2a. A conserved sequence domain mimicks full-length ZFAS1 and its mutation cancels activity. 29475982
2011-07-21 16:46:00 knockdown of Zfas1 in a mammary epithelial cell line resulted in increased cellular proliferation and differentiation[ Zfas1 ] 21460236

名称对应

Type IDs
Synonymous 1500012F01Rik, Zfos1
Gene
Nucleutide sequences
Protein sequencees
Others
UniGene: Mm.391959

全选

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研究热度

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