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68938 Aspscr1

68938

Aspscr1

alveolar soft part sarcoma chromosome region, candidate 1 (human)

protein-coding

Mus musculus

基因描述

Type Description
Definition alveolar soft part sarcoma chromosome region, candidate 1 (human)

研究结论

Date Results Publications
2021-04-13 10:15:00 TUG is a calpain-10 substrate involved in the translocation of GLUT4 in adipocytes. 32698137
2015-08-29 10:42:00 Insulin acts through TUG proteins to control IRAP targeting, similar to GLUT4; the activity of vasopressin, an IRAP substrate, is reduced in mice with disrupted TUG action in muscle. 25944897
2015-02-14 12:17:00 A conditional expression in mice of the fusion gene ASPSCR1-TFE3 from human alveolar soft part sarcoma (ASPS) generated a model that recapitulates the human tumor histologically and by expression profile. 25453902
2013-09-28 11:51:00 Data indicate that insulin stimulates proteolysis of TUG (tether containing a ubiquitin regulatory X (UBX) domain for glucose transporter 4 (GLUT4)) to translocate GLUT4 in muscle. 23744065
2012-10-13 10:09:00 Data suggest a model whereby insulin stimulates TUG cleavage to liberate GLUT4 storage vesicles from the Golgi matrix, which promotes GLUT4 translocation to the cell surface and enhances glucose uptake. 22610098

名称对应

Type IDs
Synonymous 1190006K01Rik, ASPC, ASPCR1, ASPL, ASPS, RCC17, TUG
Gene
UniProtKB-ID: ASPC1_MOUSE
UniprotKB: Q8VBT9
UniParc: UPI000004EF24, UPI00005AC4C7, UPI000002870A
EMBL: AY349132, BC031153, BC022115, AY349133, AL663030, AK004509, BC019177, AK146061
Ensembl: ENSMUSG00000025142
KO: mmu:68938
Nucleutide sequences
EMBL-CDS: BAE26870.1, AAH31153.1, BAB23341.1, AAR01614.1, AAH19177.1, AAH22115.1, AAR01613.1
Ensembl_TRS: ENSMUST00000106159, ENSMUST00000106160, ENSMUST00000103016, ENSMUST00000026135, ENSMUST00000106158
Protein sequencees
Ensembl_PRO: ENSMUSP00000026135, ENSMUSP00000101766, ENSMUSP00000099305, ENSMUSP00000101765, ENSMUSP00000101764
RefSeq: NP_001349984.1, NP_001349985.1, XP_030102126.1, XP_006534150.1, NP_001157696.1, XP_036012836.1, XP_006534149.1, NP_081153.1, XP_030102125.1, NP_937866.1
Others
UniRef100: UniRef100_Q8VBT9
UniRef90: UniRef90_Q8VBT9
UniRef50: UniRef50_Q9BZE9
UniGene: Mm.294020
CCDS: CCDS25752.1, CCDS49008.1, CCDS25751.1

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