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68916 Cdkal1

68916

Cdkal1

CDK5 regulatory subunit associated protein 1-like 1

protein-coding

Mus musculus

基因描述

Type Description
Definition CDK5 regulatory subunit associated protein 1-like 1

研究结论

Date Results Publications
2020-04-18 11:46:00 Cdkal1 catalyzes methylthiolation of t6A37 in tRNALysUUU to ms2t6A37. 31941883
2019-02-23 10:17:00 Our results identify CDKAL1 as novel negative regulator of adipocyte differentiation and provide insights into the link between CDKAL1 and metabolic diseases such as type 2 diabetes and obesity. 28779110
2018-12-22 10:28:00 Cdkal1 is necessary for normal mitochondrial morphology and function in adipose tissue. These results suggest that the type 2 diabetes susceptibility gene CDKAL1 has novel functions in regulating mitochondrial activity. 29031721
2013-03-16 11:08:00 CDKAL1 may affect such compensatory mechanisms regulating glucose homeostasis through interaction with diet 23173044
2012-02-25 10:15:00 Knockout mice with pancreatic beta-cell-specific lack of cdkal1 show pancreatic islet hypertrophy and impaired blood glucose control. 21908934

名称对应

Type IDs
Synonymous 1190005B03Rik, 6620401C13Rik
Gene
UniProtKB-ID: CDKAL_MOUSE
UniprotKB: Q91WE6
UniParc: UPI00005B25C8, UPI00005AB66D, UPI00001E85BE, UPI00000E9E09, UPI0000029387
EMBL: AL513025, AK041864, AL589701, AK045506, BC016073, AL645587, AL512647, AK004490, AK082629, AK169761
Ensembl: ENSMUSG00000006191
KO: mmu:68916
Nucleutide sequences
EMBL-CDS: BAE20608.1, CAI35144.1, BAE41351.1, BAC38554.1, CAI24675.1, BAB23330.1, AAH16073.1, CAI24677.1, BAE43325.1, CAI25816.1, CAI35240.1
Ensembl_TRS: ENSMUST00000006353, ENSMUST00000091674, ENSMUST00000140278, ENSMUST00000137225
Protein sequencees
Ensembl_PRO: ENSMUSP00000089262, ENSMUSP00000117404, ENSMUSP00000006353, ENSMUSP00000122249
RefSeq: XP_036014045.1, XP_006516826.1, XP_006516825.1, XP_017171078.1, NP_653119.1, NP_001295415.1, XP_006516827.1, XP_011242644.1, XP_017171079.1, XP_036014044.1
Others
UniRef100: UniRef100_Q91WE6
UniRef90: UniRef90_Q91WE6
UniRef50: UniRef50_Q5VV42
UniGene: Mm.212227
CCDS: CCDS84016.1, CCDS26412.1

全选

研究热度
发表文献
研究结论
热点单位
排名 科研单位 文献
1

University of Utah

2
2

Telethon Institute of Genetics and Medicine

2
3

Kumamoto University

2
4

Broad Institute MIT and Harvard

1
5

Institute of Cell Biology and Neurobiology

1
热点人员
排名 研究人员 文献
1

P Carninci

7
2

Y Hayashizaki

6
3

H Konno

5
4

K Shibata

5
5

M Itoh

5
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