| Type | Description |
|---|---|
| Definition | pygopus 2 |
| Date | Results | Publications |
|---|---|---|
| 2021-01-16 15:55:00 | A Pygopus 2-Histone Interaction Is Critical for Dedifferentiation and Progression in Malignant Breast Cancer. | 32586983 |
| 2019-02-09 11:21:00 | Our study revealed an association between Pygo2 function and obesity or diabetes. we showed that Pygo2 exhibited a declined expression pattern during adipocyte differentiation, resulting in an attenuated Wnt/beta-catenin output level. We further showed impaired glucose tolerance and decreased systemic insulin sensitivity in Pygo2-deficient mice. | 30279163 |
| 2018-02-24 11:39:00 | Suggest that Pygo2 has a tumor promoting function related to Wnt/ss-catenin signaling activity during intestinal tumor initiation and progression. | 27811361 |
| 2017-11-18 11:49:00 | Transcriptional cofactors Bcl9, Bcl9l and Pygo1/2 act independently of beta-catenin to ensure proper enamel formation. | 28174279 |
| 2015-01-17 10:43:00 | It analyzed Wnt1-cre(+/-)::Pygo2(-/-) mice in which the beta-catenin co-activator gene, Pygopus 2 (Pygo2), is deleted specifically in neural crest cells. | 23955574 |
| Type | IDs |
|---|---|
| Synonymous | 1190004M21Rik |
| Gene |
UniProtKB-ID:
Q80V76_MOUSE,
Q3V113_MOUSE
UniprotKB:
Q80V76,
Q3V113
UniParc:
UPI00001C2BFA,
UPI0000006BF4
EMBL:
BC025640,
AK132759,
AY486147,
AC171273
Ensembl:
ENSMUSG00000047824
KO:
mmu:68911
|
| Nucleutide sequences |
EMBL-CDS:
AAS55435.1,
AAH25640.1,
BAE21340.1
Ensembl_TRS:
ENSMUST00000060061,
ENSMUST00000107413
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000053672,
ENSMUSP00000103036
RefSeq:
NP_001280696.1,
NP_001280692.1,
NP_001280695.1,
XP_030108644.1,
NP_081145.1,
XP_030108645.1,
NP_001280697.1
|
| Others |
UniRef100:
UniRef100_Q80V76
UniRef90:
UniRef90_Q9BRQ0
UniRef50:
UniRef50_Q9BRQ0
UniGene:
Mm.22521
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员