| Type | Description |
|---|---|
| Definition | basic transcription factor 3 |
| Date | Results | Publications |
|---|---|---|
| 2020-07-18 12:17:00 | BTF3 is positively related to CRC and BTF3-siRNA attenuated the tumorigenicity of colorectal cancer cells via MAD2L2, MCM3 and PLK1 activity reduction. | 31263147 |
| 2020-02-15 13:09:00 | Expression of BTF3 is upregulated in hypopharyngeal squamous cell carcinoma and this upregulation is positively correlated with lymph node metastasis of this malignancy. | 31404775 |
| 2019-11-30 10:32:00 | Study showed that BTF3 is overexpressed in prostate cancer (PCa) tissues and correlates with stem-like traits. Cancer stem-like characteristics in PCa including self-renewal and metastatic potential were impaired by BTF3 loss. BTF3 could stabilize BMI1, a crucial regulator of prostate stem cell self-renewal. More importantly, data revealed that BTF3 is highly predictive of poor prognosis. | 31138311 |
| 2019-10-12 12:47:00 | TCGA analysis reveals high expression levels of BTF3 in luminal/ER + breast cancer and cell line models harboring ERalpha overexpression. Concordantly, BTF3 expression is highly and strongly associated with ESR1 expression in multiple breast cancer cohorts. | 30315845 |
| 2018-03-03 11:12:00 | Findings provide a novel understanding of the mechanism of gastric cancer and highlight the important role of BTF3/FOXM1 in tumor growth and in EMT and metastasis | 28276310 |
| Type | IDs |
|---|---|
| Synonymous | BETA-NAC, BTF3a, BTF3b, NACB |
| Gene |
UniProtKB-ID:
BTF3_HUMAN
UniprotKB:
P20290
UniParc:
UPI0000049C1C,
UPI000000067D
EMBL:
X74070,
X53280,
AK291125,
M90357,
BC008062,
BT007120,
CH471084,
X53281,
AB062126,
M90352
Ensembl:
ENSG00000145741
KO:
hsa:689
|
| Nucleutide sequences |
EMBL-CDS:
AAA58398.1,
AAP35784.1,
BAB93458.1,
CAA52200.1,
CAA37375.1,
AAH08062.1,
EAW95727.1,
CAA37376.1,
BAF83814.1
Gene_ORFName:
OK/SW-cl.8
Ensembl_TRS:
ENST00000335895,
ENST00000380591
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000369965,
ENSP00000338516
RefSeq:
NP_001198.2,
NP_001032726.1
|
| Others |
UniRef100:
UniRef100_P20290
UniRef90:
UniRef90_P20290
UniRef50:
UniRef50_P20290
UniGene:
Hs.591768
CCDS:
CCDS4019.1,
CCDS34185.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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