| Type | Description |
|---|---|
| Definition | dispatched RND transporter family member 1 |
| Date | Results | Publications |
|---|---|---|
| 2019-08-10 12:24:00 | The results showed that a protein called Furin activates Dispatched by splitting it at a specific point. When the break-point on Dispatch was genetically modified, Furin could no longer cleave the protein. As a consequence, Dispatched did not reach the correct location within cells to help Hedgehog move away from signal-releasing cells. | 29359685 |
| 2010-01-21 00:00:00 | Disp is required for the movement of Hh protein from its sites of synthesis in mice | 12421714 |
| 2010-01-21 00:00:00 | Shh signaling is required within the notochord to maintain Shh expression and to prevent notochord degeneration. Disp1, unlike Smo, is not required for this juxtacrine signaling by Shh. | 12372258 |
| 2010-01-21 00:00:00 | Disp1 regulates growth of mammalian long bones through the control of Indian hedgehog distribution. | 18395198 |
| 2010-01-21 00:00:00 | Disp1 has a role in sonic hedgehog-expressing cells for paracrine activity of the cholesterol-modified ligand | 15576405 |
| Type | IDs |
|---|---|
| Synonymous | 1190008H24Rik, DispA |
| Gene |
UniProtKB-ID:
DISP1_MOUSE
UniprotKB:
Q3TDN0
UniParc:
UPI0000022536,
UPI000000B2FA
EMBL:
BC059225,
AY150698,
AK170113,
AY150577,
AK004521,
AK138276,
BC043102,
AY144589
Ensembl:
ENSMUSG00000030768
KO:
mmu:68897
|
| Nucleutide sequences |
EMBL-CDS:
AAN08631.1,
BAE23607.1,
AAH59225.1,
BAE41571.1,
AAH43102.1,
AAN52161.1,
BAB23344.1,
AAN64660.1
Ensembl_TRS:
ENSMUST00000171366,
ENSMUST00000195372,
ENSMUST00000003035
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000141747,
ENSMUSP00000003035,
ENSMUSP00000126742
RefSeq:
NP_001265147.1,
XP_036009287.1,
NP_081142.3,
NP_001265148.1,
NP_001265149.1,
XP_006535659.1,
XP_036009288.1,
XP_036009284.1
|
| Others |
UniRef100:
UniRef100_Q3TDN0
UniRef90:
UniRef90_Q3TDN0
UniRef50:
UniRef50_Q3TDN0
UniGene:
Mm.327216,
Mm.358721
CCDS:
CCDS56661.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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