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6888 TALDO1

6888

TALDO1

transaldolase 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition transaldolase 1

研究结论

Date Results Publications
2019-01-05 12:08:00 these results pinpoint transaldolase as a novel metabolic enzyme possessing synthetic lethality with HER2 inhibition. 30323337
2018-06-16 10:48:00 These results demonstrate that the nucleocytoplasmic distribution of TALDO1, modulated via alternative translational initiation and dimer formation, plays an important role in a wide range of metabolic networks 27703206
2016-02-27 11:29:00 The above findings support the premise that biallelic mutations in TALDO1 are responsible for transaldolase deficiency and confirm the broad phenotypic variability of this condition, even with the same genotype. 25388407
2014-07-19 11:30:00 This study expands the clinical definition of transaldolase deficiency, and adds to its allelic heterogeneity. 23315216
2013-11-02 11:04:00 Data suggest that exchange reactions during gluconeogenesis catalyzed by transaldolase and triose-phosphate isomerase do not differ between subjects with type 2 diabetes and control subjects under fasting or hyperglycemic conditions. 23736541

名称对应

Type IDs
Synonymous TAL, TAL-H, TALDOR, TALH
Gene
UniProtKB-ID: TALDO_HUMAN, A0A140VK56_HUMAN
UniprotKB: P37837, A0A140VK56
UniParc: UPI00001114B0
EMBL: L19437, HM005596, AF058913, AF010399, BC018847, AF010400, AF010398, AK313427, L27346, BC010103
Ensembl: ENSG00000177156
KO: hsa:6888
Nucleutide sequences
EMBL-CDS: AAH18847.2, AAC52068.1, AAH10103.1, AAF40478.1, BAG36219.1, AAB53943.1, AAL31313.1, AEE61193.1
Ensembl_TRS: ENST00000319006
Protein sequencees
Ensembl_PRO: ENSP00000321259
RefSeq: NP_006746.1
Others
UniRef100: UniRef100_P37837
UniRef90: UniRef90_P37837
UniRef50: UniRef50_P37837
UniGene: Hs.438678
CCDS: CCDS7712.1

全选

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