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6886 TAL1

6886

TAL1

TAL bHLH transcription factor 1, erythroid differentiation factor

protein-coding

Homo sapiens

基因描述

Type Description
Definition TAL bHLH transcription factor 1, erythroid differentiation factor

研究结论

Date Results Publications
2021-03-28 19:07:00 The transcription factor TAL1 and miR-17-92 create a regulatory loop in hematopoiesis. 33293632
2020-12-12 13:22:00 The transcription factor NFE2 enhances expression of the hematopoietic master regulators SCL/TAL1 and GATA2. 32593672
2020-06-20 12:40:00 among the many factors wired within this complex regulatory network, ETV2, SCL and RUNX1 are the central components. All three factors are absolutely required for blood cell generation, each one controlling a precise step of specification from the mesoderm germ layer to fully functional blood progenitors 31432499
2020-05-23 12:47:00 Manipulation of CTCF boundary can alter TAL1 TAD and oncogenic transcription networks in leukemogenesis. 32086528
2019-11-23 10:20:00 Data indicate a T-cell acute lymphocytic leukaemia 1 (TAL1) /FUSE binding protein 1 (FUBP1) transcriptional relationship, whose physiological function in haematopoiesis is connected to proper erythropoiesis. 30653565

名称对应

Type IDs
Synonymous SCL, TCL5, bHLHa17, tal-1
Gene
UniProtKB-ID: TAL1_HUMAN, Q16509_HUMAN
UniprotKB: P17542, Q16509
UniParc: UPI00001368B2, UPI000002B4B6, UPI000006F714, UPI000002B4B5
EMBL: X58622, M61104, M63572, X58621, M63576, S53245, M63589, CH471059, X51990, M61105, M29038, M61103, M63584, M61108, AL135960
Ensembl: ENSG00000162367
KO: hsa:6886
Nucleutide sequences
EMBL-CDS: AAA36600.1, CAA41476.1, EAX06876.1, CAA41477.1, EAX06875.1, AAA36598.1, EAX06877.1, CAB72103.1, AAA36599.1, CAA36246.1, AAB19683.1
Ensembl_TRS: ENST00000294339, ENST00000371884
Protein sequencees
Ensembl_PRO: ENSP00000360951, ENSP00000294339
RefSeq: NP_003180.1, NP_001277332.1, XP_016857682.1, XP_016857677.1, XP_016857676.1, XP_016857679.1, NP_001277335.1, NP_001277333.1, NP_001274276.1, XP_005271217.1, XP_016857680.1, NP_001277334.1, XP_016857678.1, XP_016857681.1
Others
UniRef100: UniRef100_Q16509, UniRef100_P17542
UniRef90: UniRef90_P22091
UniRef50: UniRef50_P22091
UniGene: Hs.705618
CCDS: CCDS547.1

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