| Type | Description |
|---|---|
| Definition | repulsive guidance molecule family member B |
| Date | Results | Publications |
|---|---|---|
| 2020-05-23 11:36:00 | These results demonstrate an important role for a novel innate pathway in regulating type 2 inflammation in patients with allergic asthma involving RGMb and RGMb-expressing cells, such as interstitial macrophages and bronchial epithelial cells. Moreover, targeting this previously unappreciated innate pathway might provide an important treatment option for allergic asthma. | 30703386 |
| 2019-10-05 12:52:00 | These findings from the K113S variant provide not only a possible explanation for the B7-DC-triggered contradictory effects on T-cell responses, but also a novel approach to investigate the B7-DC/PD-1/RGMb axis. | 28479601 |
| 2018-08-04 11:16:00 | Specific knockout of Rgmb in tubular cells increased MLKL expression at the apical membrane of proximal tubular cells and induced more tubular cell death and more severe renal dysfunction compared with wild-type mice. | 29382757 |
| 2017-11-18 12:49:00 | Study focused on the RGMa and RGMb expression in cerebral cortex and hippocampus of newborn mice with maternal lead exposure. RGMa and RGMb expression in hippocampus were upregulated in lead exposed groups, and the RGMa and RGMb expression in cerebral cortex were also higher. | 27545491 |
| 2017-09-30 13:39:00 | These results reveal RGMb as a novel regulator for Autosomal dominant polycystic kidney disease by promoting renal tubule branching and regulating BMP signaling pathway. | 27575743 |
| Type | IDs |
|---|---|
| Synonymous | 1110059F19Rik, DRAGON |
| Gene |
UniProtKB-ID:
RGMB_MOUSE
UniprotKB:
Q7TQ33
UniParc:
UPI00001ADD99
EMBL:
AK035713,
BC138890,
AK080819,
BC096024,
AJ557514
Ensembl:
ENSMUSG00000048027
KO:
mmu:68799
|
| Nucleutide sequences |
EMBL-CDS:
AAI38891.1,
AAH96024.2,
BAC38034.1,
CAD89719.1,
BAC29163.1
Ensembl_TRS:
ENSMUST00000170578
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000126177
RefSeq:
NP_001359188.1,
NP_001359187.1,
NP_001359186.1,
NP_001359185.1,
NP_848730.2,
NP_001359221.1
|
| Others |
UniRef100:
UniRef100_Q7TQ33
UniRef90:
UniRef90_Q7TQ33
UniRef50:
UniRef50_Q7TQ33
UniGene:
Mm.293466
CCDS:
CCDS37455.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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