| Type | Description |
|---|---|
| Definition | ubiquitin protein ligase E3 component n-recognin 3 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-20 13:29:00 | Tex19.1 inhibits the N-end rule pathway and maintains acetylated SMC3 cohesin and sister chromatid cohesion in oocytes. | 32232464 |
| 2017-04-29 12:14:00 | Mouse UBR3 poly-ubiquitinates Kif7, the mammalian homologue of Cos2. Finally, loss of UBR3 up-regulates Kif7 protein levels and decreases Hh signaling in cultured cells. | 27195754 |
| 2012-03-17 10:30:00 | Knockout of the Ubr3 gene in mouse embryonic fibroblasts leads to an up-regulation of the cellular levels of APE1 protein and subsequent genomic instability. | 21933813 |
| 2010-01-21 00:00:00 | the UBR box of UBR3 may recognize small compounds that modulate the targeting, by this E3, of its currently unknown substrates | 17462990 |
| Type | IDs |
|---|---|
| Synonymous | 1110059H15Rik, 4833421P10Rik, A130030D10Rik, AA409735, AA414972, AA422631, AI646861, AU016126, Zfp650, Znf650 |
| Gene |
UniProtKB-ID:
UBR3_MOUSE,
Q8CAW0_MOUSE,
F6QC57_MOUSE
UniprotKB:
Q5U430,
Q8CAW0,
F6QC57
UniParc:
UPI0001627805,
UPI00015FA08B,
UPI00015FA08C,
UPI00000E958A,
UPI0000455F71
EMBL:
AK173334,
BC085286,
AL929249,
AK037622,
DQ924536
Ensembl:
ENSMUSG00000044308
KO:
mmu:68795
|
| Nucleutide sequences |
EMBL-CDS:
ABK59000.1,
BAD32612.1,
AAH85286.1,
BAC29837.1
Ensembl_TRS:
ENSMUST00000055758,
ENSMUST00000112251
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000060159,
ENSMUSP00000107870
RefSeq:
XP_036018421.1,
NP_808451.2,
NP_001289962.1,
XP_036018419.1,
XP_006500183.2,
XP_036018420.1
|
| Others |
UniRef100:
UniRef100_F6QC57,
UniRef100_Q8CAW0,
UniRef100_Q5U430
UniRef90:
UniRef90_Q5U430,
UniRef90_Q8CAW0
UniRef50:
UniRef50_Q8CAW0,
UniRef50_Q5U430
UniGene:
Mm.314576
CCDS:
CCDS16104.2
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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