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68792 Srpx2

68792

Srpx2

sushi-repeat-containing protein, X-linked 2

protein-coding

Mus musculus

基因描述

Type Description
Definition sushi-repeat-containing protein, X-linked 2

研究结论

Date Results Publications
2020-12-05 13:00:00 The endogenous neuronal complement inhibitor SRPX2 protects against complement-mediated synapse elimination during development. 32661396
2020-07-18 12:11:00 Unsupervised hierarchical clustering using SRPX2 expression did not identify genotype or injury-specific clusters. Data demonstrate that SRPX2 expression in the hypothalamus is resistant to genetic deficiencies in the urokinase-system or to the hypothalamus-affecting TBI. 31362033
2019-04-13 10:05:00 we show that mice lacking SRPX2 show a specific reduction in excitatory VGlut2 synapses in the cerebral cortex, while VGlut1 and inhibitory synapses were largely unaffected. SRPX2 KO mice also exhibit an abnormal ultrasonic vocalization ontogenetic profile in neonatal pups, and reduced preference for social novelty. 29920554

名称对应

Type IDs
Synonymous 1110039C07Rik, SRP, SRPUL
Gene
UniProtKB-ID: SRPX2_MOUSE
UniprotKB: Q8R054
UniParc: UPI000019322B
EMBL: BC028307, AL691421, AF393642, AF393646, AK136935, AF393641, AF393644, AF393645, AF393647, AF393640, AF393643
Ensembl: ENSMUSG00000031253
KO: mmu:68792
Nucleutide sequences
EMBL-CDS: AAM73690.1, AAM73691.1, BAE23179.1, AAH28307.1
Ensembl_TRS: ENSMUST00000113304, ENSMUST00000033606
Protein sequencees
Ensembl_PRO: ENSMUSP00000108929, ENSMUSP00000033606
RefSeq: NP_081114.2, NP_001077364.2, XP_006528669.1
Others
UniRef100: UniRef100_Q8R054
UniRef90: UniRef90_Q8R054
UniRef50: UniRef50_O60687
UniGene: Mm.263553
CCDS: CCDS41119.2

全选

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研究热度

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