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6876 TAGLN

6876

TAGLN

transgelin

protein-coding

Homo sapiens

基因描述

Type Description
Definition transgelin

研究结论

Date Results Publications
2021-04-13 10:10:00 Transgelin Silencing Induces Different Processes in Different Breast Lines. 32061197
2021-03-13 13:18:00 Transgelin is a poor prognostic factor associated with advanced colorectal cancer (CRC) stage promoting tumor growth and migration in a TGFbeta-dependent manner. 32393769
2021-02-13 13:22:00 Functional loss of TAGLN inhibits tumor growth and increases chemosensitivity of non-small cell lung cancer. 32819569
2020-02-15 10:04:00 Results indicate that TAGLN is a p53 and PTEN-upregulated gene, expressing higher levels in normal bladder epithelial cells than in carcinoma cells. Further, TAGLN inhibited cell proliferation and invasion in vitro and blocked tumorigenesis in vivo. Collectively, it can be concluded that TAGLN is an antitumor gene in the human bladder. 31591355
2019-12-07 10:31:00 SM22alpha reduction in abdominal aortic aneurysms (AAAs) because of the SM22alpha promoter hypermethylation accelerates AAA formation through the reactive oxygen species/NF-kappaB pathway. 30580562

名称对应

Type IDs
Synonymous SM22, SM22-alpha, SMCC, TAGLN1, WS3-10
Gene
UniProtKB-ID: TAGL_HUMAN, Q5U0D2_HUMAN
UniprotKB: Q01995, Q5U0D2
UniParc: UPI0000000C67
EMBL: M83106, M95787, CH471065, BT019648, AF013711, BC004927, D17409, EF445034, BC093050, D84342, CR541681, BC092415, GQ891375, AK314043, BC065829, CR749612, BT019649
Ensembl: ENSG00000149591
KO: hsa:6876
Nucleutide sequences
EMBL-CDS: BAA21839.1, AAC21582.1, BAA21811.1, AAA58351.1, AAH04927.1, AAH65829.1, AAA58375.1, BAG36752.1, CAG46482.1, AAV38455.1, EAW67301.1, AAV38454.1, EAW67299.1, ACA06080.1, AAH93050.1, AAH92415.1, CAH18406.1, ADO22237.1
Gene_ORFName: hCG_2032895
Ensembl_TRS: ENST00000278968, ENST00000392951, ENST00000530649, ENST00000525531, ENST00000532870
Protein sequencees
Ensembl_PRO: ENSP00000278968, ENSP00000431941, ENSP00000432054, ENSP00000376678, ENSP00000432282
RefSeq: NP_003177.2, NP_001001522.1
Others
UniRef100: UniRef100_Q01995
UniRef90: UniRef90_Q01995
UniRef50: UniRef50_Q01995
UniGene: Hs.410977
CCDS: CCDS8381.1

全选

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