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68708 Rabl2

68708

Rabl2

RAB, member RAS oncogene family-like 2

protein-coding

Mus musculus

基因描述

Type Description
Definition RAB, member RAS oncogene family-like 2

研究结论

Date Results Publications
2017-09-30 11:19:00 CEP19 is recruited to the ciliary base by the centriolar CEP350/FOP complex and then specifically captures GTP-bound RABL2B, which is activated via its intrinsic nucleotide exchange. 28625565
2017-05-27 11:17:00 RABL2 dysfunction, even in mice fed a low-fat chow diet, leads to retarded hepatic mitochondria movement associated with and a cascading phenotype of interrelated metabolic defects reminiscent of a type 2 diabetic state: hepatic steatosis, insulin resistance, glucose intolerance, and adult onset obesity. 27732084
2013-03-23 10:31:00 Our data demonstrate a novel function for the RABL protein family, an essential role for RABL2 in male fertility and a previously uncharacterised mechanism for protein delivery to the flagellum. 23055941

名称对应

Type IDs
Synonymous 1110031N17Rik, AW549303, Rabl2a
Gene
UniProtKB-ID: RBL2A_MOUSE
UniprotKB: E9Q9D5
UniParc: UPI0000D8B0DF, UPI0000029A37, UPI0000195780
EMBL: BC030376, AC122401, AK170205, AK004012
Ensembl: ENSMUSG00000022621
KO: mmu:68708
Nucleutide sequences
EMBL-CDS: BAE41635.1, AAH30376.1, BAB23123.1
Ensembl_TRS: ENSMUST00000023294, ENSMUST00000094056
Protein sequencees
Ensembl_PRO: ENSMUSP00000091598, ENSMUSP00000023294
RefSeq: XP_006521389.1, XP_030104587.1, NP_081093.2, XP_036015456.1, XP_006521390.1, XP_036015457.1, XP_030104590.1
Others
UniRef100: UniRef100_E9Q9D5
UniRef90: UniRef90_E9Q9D5
UniRef50: UniRef50_Q9UNT1
UniGene: Mm.23258
CCDS: CCDS49704.1

全选

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研究热度

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