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6869 TACR1

6869

TACR1

tachykinin receptor 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition tachykinin receptor 1

研究结论

Date Results Publications
2020-10-24 14:05:00 SP/NK-1R promotes gallbladder cancer cell proliferation and migration. 30903649
2020-09-05 13:58:00 TGFbeta regulates NK1R-Tr to affect the proliferation and apoptosis of breast cancer cells. 32380077
2020-08-29 12:48:00 The neuropeptide substance P regulates aldosterone secretion in human adrenals. 32471973
2020-07-25 11:03:00 The significant role of NK1R in mediating ESCC cell proliferation depended on the activation of SP and might be related to the downstream regulation of Hes1. 31109645
2020-07-11 10:10:00 was highly expressed in neuroblastoma tissues. duanyu1748P knockdown inhibited proliferation, migration and invasion in neuroblastoma cells. TACR1 was a target of miR-206 and duanyu1748P performed as a molecular sponge of miR-206 to sequester miR-206 from TACR1 in neuroblastoma cells. TACR1 overexpression abrogated the inhibitory effect of duanyu1748P downregulation on neuroblastoma cell progression by activating ERK1/2 pathway. 30582709

名称对应

Type IDs
Synonymous NK1R, NKIR, SPR, TAC1R
Gene
UniProtKB-ID: NK1R_HUMAN
UniprotKB: P25103
UniParc: UPI0000039D68, UPI000002AF31
EMBL: M74290, AK289765, X65178, M84426, M81797, X65181, AC007400, M84425, AY462098, CH471053, X65179, X65180, X65177, BC074911, BC074912, M76675, S62045
Ensembl: ENSG00000115353
KO: hsa:6869
Nucleutide sequences
EMBL-CDS: CAA46292.1, EAW99596.1, AAA60601.1, AAA59936.1, BAF82454.1, AAA36644.1, AAR23925.1, AAH74911.1, AAA36641.1, AAH74912.1, AAB20168.2, AAA59933.1
Ensembl_TRS: ENST00000409848, ENST00000305249
Protein sequencees
Ensembl_PRO: ENSP00000303522, ENSP00000386448
RefSeq: NP_001049.1, NP_056542.1
Others
UniRef100: UniRef100_P25103
UniRef90: UniRef90_P14600
UniRef50: UniRef50_P14600
UniGene: Hs.633301
CCDS: CCDS46345.1, CCDS1958.1

全选

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