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6867 TACC1

6867

TACC1

transforming acidic coiled-coil containing protein 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition transforming acidic coiled-coil containing protein 1

研究结论

Date Results Publications
2015-10-24 11:06:00 The correlation between TACC1 expression and HER-2-positive status indicates synergistic regulation of these two prognostic markers in gastric carcinoma patients. 25297519
2014-10-04 10:58:00 TFF3 and TACC1 over-expression in epithelial cells of surgically resected gastric cancer tissues was an independent predictor of short survival in gastric cancer patients. 24358147
2013-09-14 10:46:00 These findings provide proof and the foundation for the molecular and biological relationships of ErbB-2 and TACC1 in breast cancer. 23354013
2012-11-24 10:38:00 study reports that a small subset of glioblastoma multiforme tumors harbors oncogenic chromosomal translocations that fuse in-frame the tyrosine kinase coding domains of fibroblast growth factor receptor genes(FGFR1 or FGFR3) to the transforming acidic coiled-coil coding domains of TACC1 or TACC3; the FGFR-TACC fusion protein displays oncogenic activity 22837387
2011-08-06 11:13:00 the study demonstrated that TACC1 localizes at the midbody during cytokinesis and interacts with and is a substrate of Aurora-C, which warrant further investigation in order to elucidate the functional significance of this interaction. 21531210

名称对应

Type IDs
Synonymous Ga55
Gene
UniProtKB-ID: TACC1_HUMAN, E7EVI4_HUMAN, Q5HYH0_HUMAN
UniprotKB: O75410, E7EVI4, Q5HYH0
UniParc: UPI0005CFFA90, UPI00004C2D4F, UPI00002108F6, UPI00004C413E, UPI00004C2D50, UPI0000247054, UPI0005CFFF9E, UPI000013DACE, UPI0000424D09, UPI00002108F3, UPI0000074117, UPI0001E8F3C2
EMBL: BC041391, CH471080, AF049910, BX647696, AY177411, AY039239, AY139007, AY072876, AC067817, AB029026, AC016813, AY072874, AY072875, AK314620, AK304507
Ensembl: ENSG00000147526
KO: hsa:6867
Nucleutide sequences
EMBL-CDS: AAH41391.1, AAO53446.1, AAN28955.1, AAK68658.1, BAG65314.1, EAW63296.1, AAL62461.1, EAW63298.1, AAC32327.1, AAL62462.1, EAW63293.1, BAG37186.1, AAL62463.2, BAA83055.1, CAI46025.1
Ensembl_TRS: ENST00000520615, ENST00000317827, ENST00000276520, ENST00000518415, ENST00000520973
Protein sequencees
Ensembl_PRO: ENSP00000428706, ENSP00000276520, ENSP00000321703, ENSP00000428450, ENSP00000430959
RefSeq: NP_001116296.1, NP_001339726.1, XP_011542937.1, XP_011542934.1, NP_001339732.1, NP_001139688.1, NP_001339711.1, NP_001339729.1, NP_001339723.1, NP_001339714.1, XP_005273686.1, NP_001339718.1, NP_001339724.1, NP_001339720.1, NP_001339721.1, NP_001339707.1, NP_001339733.1, XP_005273682.1, NP_001339727.1, NP_006274.2, NP_001339725.1, NP_001339717.1, NP_001339715.1, NP_001339710.1, NP_001317450.1, NP_001339719.1, NP_001339709.1, XP_011542938.1, NP_001339731.1, NP_001339728.1, NP_001339716.1, XP_005273685.1, NP_001339712.1, NP_001339722.1, NP_001339708.1, NP_001339713.1, NP_001339730.1
Others
UniRef100: UniRef100_O75410, UniRef100_E7EVI4, UniRef100_Q5HYH0
UniRef90: UniRef90_E7ET87, UniRef90_O75410
UniRef50: UniRef50_A0A1L8H2C9, UniRef50_O75410
UniGene: Hs.279245
CCDS: CCDS6109.1, CCDS47845.1, CCDS87601.1, CCDS55224.1

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