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68668 Klk5

68668

Klk5

kallikrein related-peptidase 5

protein-coding

Mus musculus

基因描述

Type Description
Definition kallikrein related-peptidase 5

研究结论

Date Results Publications
2021-01-09 13:26:00 Exacerbated dandruff in the absence of kallikrein-related peptidase 5 protease. 31912553
2020-05-30 11:56:00 The epidermis of Klk5-/- mice displays increased number of desmosomes and enhanced mechanical strength. The Klk5-/- mice are resistant to chemically-induced skin tumorigenesis. 31381994
2017-05-27 10:57:00 Ablation of KLK5 is not sufficient to rescue the lethal effect of LEKTI-deficiency. Double deficiency of both KLK5 and KLK7 completely rescues Netherton Syndrome-like phenotype. 28095415
2016-12-17 11:28:00 the pruritogenic action of KLK5 may be primarily mediated by PAR2 receptors 26268952
2016-06-04 10:18:00 findings illustrate the crucial role of protease regulation in skin homeostasis and inflammation, and establish KLK5 inhibition as a major therapeutic target for NS 26390218

名称对应

Type IDs
Synonymous 1110030O19Rik
Gene
UniProtKB-ID: Q9D140_MOUSE
UniprotKB: Q9D140
UniParc: UPI0000029A44
EMBL: AK003996, AC134858, LT631599, BC139478, BC139475
Ensembl: ENSMUSG00000074155
KO: mmu:68668
Nucleutide sequences
EMBL-CDS: AAI39479.1, SFW93246.1, BAB23113.1, AAI39476.1
Ensembl_TRS: ENSMUST00000048444
Protein sequencees
Ensembl_PRO: ENSMUSP00000049339
RefSeq: XP_006541215.1, NP_081082.1, XP_036009294.1, XP_036009295.1, XP_006541214.1, XP_006541213.1
Others
UniRef100: UniRef100_Q9D140
UniRef90: UniRef90_Q9D140
UniRef50: UniRef50_Q9D140
UniGene: Mm.458122

全选

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研究热度

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