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6866 TAC3

6866

TAC3

tachykinin 3

protein-coding

Homo sapiens

基因描述

Type Description
Definition tachykinin 3

研究结论

Date Results Publications
2020-09-12 16:02:00 Endocytic recycling prevents copper accumulation in astrocytoma cells stimulated with copper-bound neurokinin B. 31952788
2019-01-12 10:24:00 The administration of an NK3R antagonist indicates a role for Neurokinin B in the regulation of luteinising hormone (LH)/gonadotropin-releasing hormone (GnRH) in postmenopausal women, whereas the lack of response to kisspeptin may reflect the hypo-oestrogenic state. These data support a link of LH/GnRH pulsatility and vasomotor symptoms with NK3R antagonism as a potential therapeutic approach. 28380486
2018-03-24 12:01:00 Data suggest that basal serum neurokinin B level can be used as an adjunctive parameter to differentiate idiopathic central precocious puberty (ICPP) from premature thelarche (PT). 28008860
2017-07-01 11:05:00 acts through NK3 receptors in granulosa cells to stimulate steroid production 27580802
2016-03-26 11:19:00 mutations in TAC and TACR3 are not a common cause for ICPP. 24802197

名称对应

Type IDs
Synonymous HH10, NKB, NKNB, PRO1155, ZNEUROK1
Gene
UniProtKB-ID: TKNK_HUMAN, A0A024RB47_HUMAN, A0A024RB97_HUMAN
UniprotKB: Q9UHF0, A0A024RB47, A0A024RB97
UniParc: UPI00001BE8AC, UPI00000312E8, UPI0000047810
EMBL: AF537113, AF537117, CR457193, AF537119, AF537115, CH471054, AF216586, AF537121, AF537114, AF537118, AF537120, AF537116, AY358679, AF186112, BC032145
Ensembl: ENSG00000166863
KO: hsa:6866
Nucleutide sequences
EMBL-CDS: AAF01430.1, CAG33474.1, AAQ10786.1, AAH32145.1, AAQ10784.1, AAQ10783.1, AAQ10787.1, AAF76980.1, AAQ10789.1, AAQ89042.1, AAQ10788.1, AAQ10785.1, AAQ10790.1, AAQ10791.1, EAW96976.1, EAW96979.1, EAW96972.1, EAW96975.1, EAW96980.1, EAW96973.1
Gene_ORFName: UNQ585/PRO1155, hCG_2039621, hCG_2039621
Ensembl_TRS: ENST00000423597, ENST00000357616, ENST00000438756, ENST00000379411, ENST00000615887, ENST00000458521, ENST00000300108, ENST00000393867, ENST00000415231, ENST00000441881
Protein sequencees
Ensembl_PRO: ENSP00000408208, ENSP00000377445, ENSP00000404056, ENSP00000483110, ENSP00000350236, ENSP00000408131, ENSP00000402995, ENSP00000368721, ENSP00000416292, ENSP00000300108
RefSeq: NP_037383.1, NP_001171525.1
Others
UniRef100: UniRef100_A0A024RB97, UniRef100_Q9UHF0
UniRef90: UniRef90_Q9UHF0
UniRef50: UniRef50_Q9UHF0
UniGene: Hs.9730
CCDS: CCDS8928.1, CCDS53803.1

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