| Type | Description |
|---|---|
| Definition | TGF-beta activated kinase 1/MAP3K7 binding protein 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-11-21 13:13:00 | TET2 promotes IL-1beta expression in J774.1 cell through TLR4/MAPK signaling pathway with demethylation of TAB2 promoter. | 32823238 |
| 2020-03-14 10:25:00 | miR-142-3p was up-regulated both in lipopolysaccharide-induced acute lung Injury mice model and RAW264.7cells model. MiR-142a-3p mimics group experienced significant decrease in the secretion of pro-inflammatory cytokines as a result of the inhibition of NF-kappaB signaling pathway. Bioinformatics database showed that the adaptor protein, TAB2, was critical in this pathway and it is the target gene of miR-142a-3p. | 31494298 |
| 2019-07-20 11:38:00 | Lipopolysaccharide-induced miR-155 promoted autophagy to increase osteoclast formation via decreased TAB2. | 30144578 |
| 2017-04-15 11:48:00 | These findings support a regulatory role for TGF-beta-activated kinase 1 in governing downstream MAPKs/NF-kappaB signaling cascades in the macrophage activation in response to hyperglycemic insult | 27153994 |
| 2015-12-12 11:36:00 | RNF4 negatively regulates NF-kappaB signaling by down-regulating TAB2 | 26299341 |
| Type | IDs |
|---|---|
| Synonymous | 1110030N06Rik, A530078N03Rik, Map3k7ip2, mKIAA0733 |
| Gene |
UniProtKB-ID:
TAB2_MOUSE
UniprotKB:
Q99K90
UniParc:
UPI0000021417
EMBL:
AY093701,
AK089164,
AK147830,
AB093262,
BC004813,
BC004072
Ensembl:
ENSMUSG00000015755
KO:
mmu:68652
|
| Nucleutide sequences |
EMBL-CDS:
AAH04813.1,
AAM10487.1,
BAE28166.1,
AAH04072.1,
BAC41446.1,
BAC40772.1
Ensembl_TRS:
ENSMUST00000146444
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000121266
RefSeq:
NP_001346463.1,
XP_036011868.1,
XP_030101107.1,
XP_036011869.1,
XP_011241506.1,
XP_036011867.1,
XP_011241505.1,
XP_036011870.1,
XP_036011866.1,
NP_619608.1
|
| Others |
UniRef100:
UniRef100_Q99K90
UniRef90:
UniRef90_Q9NYJ8
UniRef50:
UniRef50_Q9NYJ8
UniGene:
Mm.193041
CCDS:
CCDS23691.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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