| Type | Description |
|---|---|
| Definition | T-box transcription factor T |
| Date | Results | Publications |
|---|---|---|
| 2021-02-13 13:22:00 | Inhibition of Histone H3K27 Demethylases Inactivates Brachyury (TBXT) and Promotes Chordoma | 32855205 |
| 2020-03-28 12:02:00 | Signifying their developmental function, the key mesoderm specifier BRACHYURY (T) is accompanied by yylncT, which localizes to the active T locus during mesoderm commitment. | 30554961 |
| 2020-03-28 11:12:00 | hordomas can be primarily diagnosed by fine needle aspiration cytology in a typical clinicoradiological setting with a combination of key cytomorphological features...An exact diagnosis has treatment implications and requires confirmation by brachyury immunostaining. | 30218622 |
| 2019-09-14 10:51:00 | Activation of the PI3K/Akt pathway and Brachyury copy number gain are strongly associated with Brachyury overexpression, which appears to be a key event in chordoma growth regulation. These findings suggest that targeting Brachyury and PI3K/Akt signaling may be an effective new approach for treating chordoma. | 28753115 |
| 2019-03-30 11:19:00 | these results indicate that Brachyury plays an oncogenic role in testicular germ cell tumors | 29749711 |
| Type | IDs |
|---|---|
| Synonymous | SAVA, T, TFT |
| Gene |
UniProtKB-ID:
TBXT_HUMAN
UniprotKB:
O15178
UniParc:
UPI0000D61512,
UPI0000126AB5
EMBL:
AJ001699,
AL627443,
BC098425
Ensembl:
ENSG00000164458
KO:
hsa:6862
|
| Nucleutide sequences |
EMBL-CDS:
CAA04938.1,
AAH98425.1
Ensembl_TRS:
ENST00000296946,
ENST00000366871
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000355836,
ENSP00000296946
RefSeq:
NP_003172.1,
NP_001257413.1,
NP_001353215.1,
NP_001353214.1
|
| Others |
UniRef100:
UniRef100_O15178
UniRef90:
UniRef90_O15178
UniRef50:
UniRef50_P20293
UniGene:
Hs.389457,
Hs.742027
CCDS:
CCDS5290.1,
CCDS59045.1
|
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|---|---|---|---|---|---|---|---|---|
| Refseq |
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