| Type | Description |
|---|---|
| Definition | shugoshin 2A |
| Date | Results | Publications |
|---|---|---|
| 2018-02-03 11:49:00 | By promoting proteolysis of cyclins and Cdc25B at germinal vesicle stage, APC/C associated Cdh1(APC/CCdh1) delays increase in Cdk1 activity, leading to germinal vesicle breakdown (GVBD); by moderating the rate at which Cdk1 is activated following GVBD, APC/CCdh1 creates conditions necessary for the removal of shugoshin-2 from chromosome arms by Aurora B/C kinase, an event crucial for efficient resolution of chiasmata. | 28502659 |
| 2017-09-30 12:13:00 | Molecular chaperone SET-assisted eviction of linker histones and Shugoshins is a fundamental step in mammalian mitotic progression. | 28781233 |
| 2017-07-01 12:04:00 | In mouse, Sgol2a encoding shugoshin-like 2a is necessary during meiosis in both sexes to maintain the integrity of the cohesin complex that tethers sister chromatids. Human SGO2 has not previously been implicated in any disorder, but in this case of POI and perhaps others, it is a candidate for unexplained infertility. | 27629923 |
| 2016-06-11 11:56:00 | Sgo2 localizes at the subtelomeres preferentially during G2 phase and is essential for the formation of a highly condensed subtelomeric chromatin body 'knob'. | 26804021 |
| 2010-01-21 00:00:00 | Results show that shugoshin Sgo2 is expressed in germ cells. | 18084284 |
| Type | IDs |
|---|---|
| Synonymous | 1110007N04Rik, 4932411A20Rik, 5730576N04Rik, AU018846, AV008062, D1Ertd8e, Sgol2, Sgol2a, Tripin |
| Gene |
UniProtKB-ID:
SGO2_MOUSE
UniprotKB:
Q7TSY8
UniParc:
UPI000019B09D
EMBL:
AK042448,
BC052742,
BC023855,
BC044797,
AK017868
Ensembl:
ENSMUSG00000026039
KO:
mmu:68549
|
| Nucleutide sequences |
EMBL-CDS:
AAH23855.1,
AAH44797.1,
BAB30980.1,
BAC31263.1,
AAH52742.1
Ensembl_TRS:
ENSMUST00000027202
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000027202
RefSeq:
NP_001171338.1,
NP_950172.1
|
| Others |
UniRef100:
UniRef100_Q7TSY8
UniRef90:
UniRef90_Q7TSY8
UniRef50:
UniRef50_Q7TSY8
UniGene:
Mm.32800
CCDS:
CCDS35574.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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