| Type | Description |
|---|---|
| Definition | transmembrane protein 109 |
| Date | Results | Publications |
|---|---|---|
| 2017-08-26 11:06:00 | Data, including data from studies in vesicles of knockout mice, suggest pathophysiological levels of Zn2+ (>2nM) cause dysregulation of RyR2 opening; in sarcoplasmic reticulum, RyR2 are not the only Ca2+-channels regulated by Zn2+; in cardiomyocytes exposed to ischemic/hypoxic conditions, intracellular Zn2+ levels are elevated, coinciding with increased MG23 expression. (RyR2 = ryanodine receptor 2; MG23 = mitsugumin 23) | 28630041 |
| 2013-06-15 11:35:00 | MG23 plays a protective role against UVC by accumulating alphaBC in the close vicinity of the ER | 23542032 |
| 2010-03-22 11:07:00 | MG23 is an essential component of ER-generated lethal signals provoked upon DNA damage, specifying cell fate under pathophysiological conditions. | 20060811 |
| Type | IDs |
|---|---|
| Synonymous | 1110006I15Rik, AA958958, C77652 |
| Gene |
UniProtKB-ID:
TM109_MOUSE
UniprotKB:
Q3UBX0
UniParc:
UPI00000245DB
EMBL:
AK151850,
AK152419,
BC023901,
BC025815,
BC025033,
AK165990,
AK150779,
BC022997
Ensembl:
ENSMUSG00000034659
KO:
mmu:68539
|
| Nucleutide sequences |
EMBL-CDS:
BAE31204.1,
AAH22997.1,
BAE30740.1,
BAE29844.1,
AAH23901.1,
AAH25033.1,
BAE38505.1,
AAH25815.1
Ensembl_TRS:
ENSMUST00000038128
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000039529
RefSeq:
NP_598903.1,
XP_006527380.1
|
| Others |
UniRef100:
UniRef100_Q3UBX0
UniRef90:
UniRef90_Q3UBX0
UniRef50:
UniRef50_O77751
UniGene:
Mm.251890
CCDS:
CCDS29590.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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