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68527 Ucma

68527

Ucma

upper zone of growth plate and cartilage matrix associated

protein-coding

Mus musculus

基因描述

Type Description
Definition upper zone of growth plate and cartilage matrix associated

研究结论

Date Results Publications
2021-03-20 13:28:00 Unique cartilage matrix-associated protein inhibits the migratory and invasive potential of triple-negative breast cancer. 32768190
2019-12-28 10:55:00 Downstream target genes of Ucma were found in osteoblasts by microarray analysis. 45 genes including Fbn2 were dependent on Ucma overexpression or knockdown. Fbn2 expression was proportional to Ucma expression in osteoblasts. 30791984
2019-10-12 11:08:00 Study using Ucma/GRP-/- and ApoE-/- mice showed for the first-time evidence of a direct interaction between Ucma/GRP and Bmp-2. These results demonstrate an important role of Ucma/GRP in regulating osteo/chondrogenic differentiation and phosphate-induced mineralisation of vascular smooth muscle cells. 29563538
2019-04-20 11:02:00 Upper zone of growth plate and cartilage matrix associated protein (Ucma) physically interacted with a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 5 (aggrecanase-2) protein (ADAMTS5) and blocked its aggrecanase activity in chondrocyte cultures. 29720262
2015-04-25 10:25:00 Data suggest that a novel splice variant of GRP is expressed in cartilage and other tissues (i.e. GRP-F7); GRP-F1 is predominant splice variant expressed in adult tissues. 24867294

名称对应

Type IDs
Synonymous 1110017I16Rik, AW121955, Grp
Gene
UniProtKB-ID: UCMA_MOUSE
UniprotKB: Q14BU0
UniParc: UPI00001EE70A, UPI000015F900, UPI0000029ACB, UPI0001B7CC7B
EMBL: FJ217398, BC115608, AK003750, EF529510, FJ217397, AL928662, EU368184, FJ217399, CH466542, BX682541, BC115609, FJ217400
Ensembl: ENSMUSG00000026668
KO: mmu:68527
Nucleutide sequences
EMBL-CDS: ABP88975.1, EDL07955.1, ACO35749.1, BAB22978.2, ACO35748.1, AAI15609.1, ACO35747.1, ABY65726.1, AAI15610.1, ACO35746.1
Ensembl_TRS: ENSMUST00000167607, ENSMUST00000027978, ENSMUST00000115010, ENSMUST00000195688
Protein sequencees
Ensembl_PRO: ENSMUSP00000141304, ENSMUSP00000027978, ENSMUSP00000126371, ENSMUSP00000110662
RefSeq: NP_081030.1, NP_001107030.1, NP_001298137.1, NP_001159404.1
Others
UniRef100: UniRef100_Q14BU0
UniRef90: UniRef90_Q14BU0
UniRef50: UniRef50_Q14BU0
UniGene: Mm.27791
CCDS: CCDS84467.1, CCDS50489.1, CCDS50490.1, CCDS15661.1

全选

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