| Type | Description |
|---|---|
| Definition | integrin subunit alpha 2b |
| Date | Results | Publications |
|---|---|---|
| 2019-01-19 12:07:00 | TNF-alpha decreases calcium internal mobilization and calcium influx in platelets. TNF-alpha significantly reduced (Tyr 416)-c-Src and (Tyr773)-beta3 subunit of integrin alphaIIbbeta3 phosphorylation. | 30359790 |
| 2017-01-28 10:32:00 | Taken together, our results reveal that ND-1 is a novel antagonist of alphaIIb3 with strong antithrombotic effect and lower bleeding risk. | 28097150 |
| 2013-04-13 10:54:00 | PI3K/Akt signaling is utilized by alphaIIb-mediated outside-in signaling to activate platelets. | 23082158 |
| Type | IDs |
|---|---|
| Gene | |
| Nucleutide sequences | |
| Protein sequencees |
RefSeq:
XP_008774041.1,
XP_017453209.1,
XP_001063315.1
|
| Others |
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 30359790 |
Thromb. Res. Pedro H L Bonfitto , Ana C Antunes Naime , M Elisa Lopes-Pires , Gisele Goulart , Camila B Mendes-Silverio , Paulo I Bueno , Roger F Castilho , Edson Antunes , Sisi Marcondes |
2018-12-01 | - |
| 28097150 |
Biomed Res Int Xue Ding , Tong-Dan Liu , Zhou-Ling Xie , Qi Zhao , Yuan Cao , Xiao-Dong Liu , Cai-Hui Wang , Rwibasira Rudinga Gamariel , Xin Ming , Zhi-Yu Li , Yi Kong |
2016-01-01 | - |
| 23912132 |
Blood Coagul. Fibrinolysis Alireza Farsinejad , Mohammad M Farajollahi , Ahmad Kazemi , Nazanin Saemi , Mohammad Faranoush |
2013-09-01 |
Itgb3,
Itga2b
|
| 23382103 |
Mol Cell Proteomics Julia Fröbel , Ron-Patrick Cadeddu , Sonja Hartwig , Ingmar Bruns , Christian M Wilk , Andrea Kündgen , Johannes C Fischer , Thomas Schroeder , Ulrich G Steidl , Ulrich Germing , Stefan Lehr , Rainer Haas , Akos Czibere |
2013-05-01 | - |
| 22394243 |
Platelets Xavier Pillois , Mathieu Fiore , Roland Heilig , Marta Pico , Alan T Nurden |
2013-01-01 |
Itga2b
|
| 22516433 |
J Proteomics Patricia Bastos-Amador , Felix Royo , Esperanza Gonzalez , Javier Conde-Vancells , Laura Palomo-Diez , Francesc E Borras , Juan M Falcon-Perez |
2012-06-27 |
ZNF559-ZNF177,
CIB2,
CFHR3,
ACSM1,
CLU,
CLIC1,
SERPINA3,
A1BG,
CP,
CPN2,
AFM,
AGT,
AHSG,
STOM,
ALB,
F2,
F13A1,
FCN2,
A2M,
FGA,
FGB,
FGG,
FN1,
DNPEP,
ZBTB38,
AMBP,
GC,
IGKV1-5,
IGHV3-23,
IGKV3D-11,
IGKV1D-33,
IGKV4-1,
IGKV3-20,
IGKV2-40,
GSN,
HBA1,
HBA2,
HBB,
HBD,
HBE1,
HBG2,
CFH,
CFHR1,
HP,
HPR,
APCS,
HPX,
HRG,
HSPA1A,
HSPA1B,
HSPA1L,
HSPA2,
HSPA6,
HSPA7,
HSPA8,
APOA1,
APOA2,
APOA4,
APOE,
IGHA1,
IGHA2,
IGHD,
IGHG1,
IGHG2,
IGHG3,
IGHG4,
IGHM,
JCHAIN,
IGKC,
IGLC1,
IGLC2,
ITGA2B,
ITIH1,
ITIH2,
ITIH4,
KNG1,
KRT1,
LGALS3BP,
LOC440786,
POTEE,
MSN,
SERPINC1,
ORM1,
ORM2,
ANGPTL4,
OAZ3,
PFN1,
PLG,
SERPINF2,
PON1,
CPSF3L,
KDM4D,
PROS1,
PRSS1,
GRIPAP1,
PSMC5,
ACTA1,
PZP,
BCHE
|
| 23082158 |
Integrin αIIb-mediated PI3K/Akt activation in platelets. PLoS One Haixia Niu , Xue Chen , Ralph A Gruppo , Ding Li , Yanhua Wang , Lin Zhang , Kemin Wang , Weiran Chai , Yueping Sun , Zhongren Ding , T Kent Gartner , Junling Liu |
2012-01-01 | - |
| 21454453 |
Blood Shinji Kunishima , Hirokazu Kashiwagi , Makoto Otsu , Naoya Takayama , Koji Eto , Masafumi Onodera , Yuji Miyajima , Yasushi Takamatsu , Junji Suzumiya , Kousaku Matsubara , Yoshiaki Tomiyama , Hidehiko Saito |
2011-05-19 | - |
| 21029361 |
J. Thromb. Haemost. W Mansour , Y Einav , H Hauschner , A Koren , U Seligsohn , N Rosenberg |
2011-01-01 |
Itga2b,
ITGA2B
|
| 20228271 |
Contrasting effects of Sox17- and Sox18-sustained expression at the onset of blood specification. Blood Alicia G Serrano , Arnaud Gandillet , Stella Pearson , Georges Lacaud , Valerie Kouskoff |
2010-05-13 | - |
| 排名 | 科研单位 | 文献 |
|---|---|---|
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| 排名 | 研究人员 | 文献 |
|---|---|---|
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