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6847 SYCP1

6847

SYCP1

synaptonemal complex protein 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition synaptonemal complex protein 1

研究结论

Date Results Publications
2019-08-17 10:23:00 SYCP1 has an obligate tetrameric structure in which an N-terminal four-helical bundle bifurcates into two elongated C-terminal dimeric coiled-coils. This building block assembles into a zipper-like lattice through two self-assembly sites. N-terminal sites undergo cooperative head-to-head assembly in the midline, while C-terminal sites interact back to back on the chromosome axis. 29915389
2017-08-05 11:21:00 Crystal structure of C-terminal coiled-coil domain of SYCP1 reveals non-canonical anti-parallel dimeric structure of transverse filament at the synaptonemal complex. 27548613
2016-07-02 11:20:00 crystal structure of the middle part of the human synaptonemal complex protein 1 coiled-coil domain 26323297
2015-09-05 11:13:00 SYCP1, cTAGE1, and GTSF1 are expressed in cutaneous T-cell lymphoma, but not in normal skin or benign inflammatory dermatoses. 24850846
2012-09-11 11:17:00 Cancer-Testis Antigen SCP-1 mRNA is expressed in some nasopharyngeal carcinoma. 17608150

名称对应

Type IDs
Synonymous CT8, HOM-TES-14, SCP-1, SCP1
Gene
UniProtKB-ID: SYCP1_HUMAN, A0A087WZC3_HUMAN, B7ZLS9_HUMAN, A0A024R0I2_HUMAN
UniprotKB: Q15431, A0A087WZC3, B7ZLS9, A0A024R0I2
UniParc: UPI000189A753, UPI0001892C14, UPI00001CE3B9
EMBL: CH471122, HM005504, AL645502, D67035, BC144019, X95654, BC126266, AL358372
Ensembl: ENSG00000198765
KO: hsa:6847
Nucleutide sequences
EMBL-CDS: CAA64956.1, BAA22586.1, AAI26267.1, EAW56622.1, AAI44020.1, EAW56623.1, AEE61101.1
Gene_ORFName: hCG_38460
Ensembl_TRS: ENST00000369522, ENST00000369518, ENST00000618516, ENST00000613524
Protein sequencees
Ensembl_PRO: ENSP00000480997, ENSP00000358535, ENSP00000358531, ENSP00000482532
RefSeq: XP_006710922.1, XP_016857673.1, NP_001269470.1, XP_016857674.1, XP_011540339.1, XP_005271213.1, NP_001269471.1, XP_011540340.1, NP_003167.2, XP_005271212.1, XP_011540341.1
Others
UniRef100: UniRef100_Q15431, UniRef100_A0A087WZC3, UniRef100_B7ZLS9
UniRef90: UniRef90_Q15431
UniRef50: UniRef50_Q62209
UniGene: Hs.112743
CCDS: CCDS879.1

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