| Type | Description |
|---|---|
| Definition | protein phosphatase 1, regulatory inhibitor subunit 14A |
| Date | Results | Publications |
|---|---|---|
| 2020-05-16 11:14:00 | upregulation of CPI-17-mediated calcium-sensitized vasocontraction by obesity contributes to the development of obesity-related hypertension | 30948334 |
| 2020-01-25 10:47:00 | These data provide a novel mechanism of the transcriptional control of CPI-17 in vascular smooth muscle cells under inflammatory conditions. Mechanistically, 2 GC boxes were identified as TNF response element in the CPI-17 promoter and KLF4 was upregulated by TNF, competed with Sp1 for the binding to the GC boxes in the CPI-17 promoter, and repressed CPI-17 transcription through histone deacetylase. | 30936247 |
| 2018-12-22 11:22:00 | CPI-17 phosphorylation at T38 is essential for the maintenance of physiological blood pressure. | 29229685 |
| 2015-07-25 10:57:00 | Enhanced vasorelaxation in early endotoxemia is mediated by redox signaling through PKG-1alpha but in later endotoxemia by myosin phosphatase isoform shifts enhancing sensitivity to NO/cGMP as well as smooth muscle atrophy. | 25724497 |
| 2013-04-13 11:55:00 | The study characterized the CPI-17 promoter and identified binding sites for GATA-6 and nuclear factor kappa B (NF-kappaB). | 23275439 |
| Type | IDs |
|---|---|
| Synonymous | 1110001M11Rik, Cpi17 |
| Gene |
UniProtKB-ID:
PP14A_MOUSE
UniprotKB:
Q91VC7
UniParc:
UPI0000026A96
EMBL:
AY050672,
AF352573,
BC010832
Ensembl:
ENSMUSG00000037166
KO:
mmu:68458
|
| Nucleutide sequences |
EMBL-CDS:
AAL25830.1,
AAH10832.1,
AAK35214.1
Ensembl_TRS:
ENSMUST00000048187
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000035642
RefSeq:
XP_036009290.1,
NP_081007.2
|
| Others |
UniRef100:
UniRef100_Q91VC7
UniRef90:
UniRef90_Q99MC0
UniRef50:
UniRef50_O18734
UniGene:
Mm.2343
CCDS:
CCDS21070.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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