| Type | Description |
|---|---|
| Definition | CREB regulated transcription coactivator 1 |
| Date | Results | Publications |
|---|---|---|
| 2019-12-07 10:24:00 | a specific deletion of mTOR in Sertoli cells was found to cause an upregulation of p-rpS6-S240/S244 (i.e., an activation of rpS6), but not total rpS6, and was associated with blood-testis barrier disruption, epithelial damage, loss of cell polarity, and infertility. | 31157869 |
| 2018-07-21 10:05:00 | The PI3K/AKT pathway in the nucleus accumbens (NAc) of rodents plays a role in the molecular and behavioral adaptations that are induced by alcohol, and that in turn drives alcohol-drinking behaviors. | 27766766 |
| 2018-03-10 10:30:00 | blockade of CRTC1-dependent gene expression in the early, preplaque phase of Alzheimer disease-like pathology provides a molecular basis for the cognitive deficits that figure so prominently in early Alzheimer disease | 26759481 |
| 2017-02-18 11:05:00 | depolarization (which produced a robust increase in Ca(2+) signals) together with cAMP signaling resulted in a synergistic induction of Pacap mRNA through calcineurin and its substrate, cAMP-response element-binding protein (CREB)-regulated transcription coactivator 1. | 27383213 |
| 2016-12-17 12:06:00 | Our results provide evidence that CREB cofactor CRTC1 translocates into the nucleus of a distinct subset of hippocampal neurons during and following status epilepticus | 26844388 |
| Type | IDs |
|---|---|
| Synonymous | Mect1, TORC-1, TORC1 |
| Gene |
UniProtKB-ID:
CRTC1_RAT
UniprotKB:
Q157S1
UniParc:
UPI0000D8A1FE
EMBL:
DQ538521
Ensembl:
ENSRNOG00000022421
KO:
rno:684527
|
| Nucleutide sequences |
EMBL-CDS:
ABG23027.1
Ensembl_TRS:
ENSRNOT00000038057
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000030925
RefSeq:
XP_006252998.1,
NP_001040580.1
|
| Others |
UniRef100:
UniRef100_Q157S1
UniRef90:
UniRef90_Q68ED7
UniRef50:
UniRef50_Q6UUV9
UniGene:
Rn.208248
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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